Padres vs. Phillies Dunkel MLB Picks, Predictions and Prop Bets - May 27

The San Diego Padres will try to snap a three-game losing streak when hosting the Philadelphia Phillies at 4:10 p.m. ET on Wednesday. Walker Buehler (3-2, 5.05 ERA) will start for the Padres, who are 31-23 this season and second in the NL West. Cristopher Sanchez (5-2, 1.62 ERA) is the expected starter for the Phillies, who are 28-27 and third in the NL East.

The moneyline odds for the Padres (-110) versus the Phillies (-109) indicate a tight game. The game's over/under is set at 7.5.

Padres vs. Phillies Odds, Game Time

• Game day: Wednesday, May 27, 2026
• Game time: 4:10 p.m. ET
• Location: San Diego, California
• Stadium: Petco Park
• Favorite: Padres (-110)
• Underdog: Phillies (-109)
• Over/under: 7.5

How to Watch Padres vs. Phillies

• TV Channel: SDPA and NBCS-PH
• Live Stream: Fubo (Watch for free)

Bet now on FanDuel Sportsbook!

Padres vs. Phillies: Betting the Moneyline

• The Padres have been favored on the moneyline 27 total times this season. They've finished 15-12 in those games.
• Philadelphia has been pegged as an underdog in 16 games this year and has walked away with the win six times (37.5%) in those games.
• San Diego has a record of 16-12, a 57.1% win rate, when favored by -110 or more by oddsmakers this season.
• This season, the Phillies have come away with a win five times in 15 chances when named as an underdog of at least -109 or longer on the moneyline.
• The Padres have an implied moneyline win probability of 52.4% in this game.
• Sportsbooks have implied with the moneyline set for this matchup that the Phillies have a 52.2% chance of pulling out a win.

Padres vs. Phillies: Betting the Spread & Total

• In the 54 games in which bookmakers have set an over/under for the Padres, they have combined with opponents to go over the total 22 times (22-30-2).
• Philadelphia and its opponents have gone over the total this season in 24 of its 55 opportunities.
• The Padres have a 31-23-0 record ATS this season (covering 57.4% of the time).
• In 55 games with a line this season, the Phillies have a mark of 18-37-0 against the spread.