NFL Predictions & Betting Odds - Week 1
09 September 2026
There are plenty of exciting matchups on the Week 1 NFL schedule, including the New England Patriots playing the Seattle Seahawks.
We've got you covered with a quick summary on every NFL tilt this week with over/unders, spreads, moneylines, and Dunkel Index predictions. Continue reading for the details.
Bet now on FanDuel Sportsbook!Week 1 Games, Betting Info, and Predictions
There are 16 games on the NFL slate this week. Here's a look at each one:
New England Patriots (0-0) at Seattle Seahawks (0-0)
- Game Time: 8:20 p.m. ET | Wednesday, September 9, 2026
- Venue: Lumen Field (Seattle, Washington)
- Total: 44.5
- Spread: Seahawks (-3.5)
- Moneyline: Seahawks (-170), Patriots (+142)
Dunkel Index predictions:
- Over/Under: Under (44.5)
- ATS: Seahawks (-3.5)
- Score Prediction: Seahawks 26, Patriots 17
San Francisco 49ers (0-0) at Los Angeles Rams (0-0)
- Game Time: 8:35 p.m. ET | Thursday, September 10, 2026
- Venue: Melbourne Cricket Ground (Melbourne, Australia)
- Total: 48.5
- Spread: Rams (-4.5)
- Moneyline: Rams (-198), 49ers (+164)
Dunkel Index predictions:
- Over/Under: Over (48.5)
- ATS: Rams (-4.5)
- Score Prediction: Rams 29, 49ers 20
Baltimore Ravens (0-0) at Indianapolis Colts (0-0)
- Game Time: 1 p.m. ET | Sunday, September 13, 2026
- Venue: Lucas Oil Stadium (Indianapolis, Indiana)
- Total: 48.5
- Spread: Ravens (-3.5)
- Moneyline: Ravens (-175), Colts (+145)
Dunkel Index predictions:
- Over/Under: Over (48.5)
- ATS: Colts (+3.5)
- Score Prediction: Colts 27, Ravens 23
Tampa Bay Buccaneers (0-0) at Cincinnati Bengals (0-0)
- Game Time: 1 p.m. ET | Sunday, September 13, 2026
- Venue: Paycor Stadium (Cincinnati, Ohio)
- Total: 50.5
- Spread: Bengals (-3.5)
- Moneyline: Bengals (-205), Buccaneers (+170)
Dunkel Index predictions:
- Over/Under: Under (50.5)
- ATS: Buccaneers (+3.5)
- Score Prediction: Buccaneers 26, Bengals 24
Atlanta Falcons (0-0) at Pittsburgh Steelers (0-0)
- Game Time: 1 p.m. ET | Sunday, September 13, 2026
- Venue: Acrisure Stadium (Pittsburgh, Pennsylvania)
- Total: 42.5
- Spread: Steelers (-3.5)
- Moneyline: Steelers (-185), Falcons (+154)
Dunkel Index predictions:
- Over/Under: Over (42.5)
- ATS: Steelers (-3.5)
- Score Prediction: Steelers 24, Falcons 21
Chicago Bears (0-0) at Carolina Panthers (0-0)
- Game Time: 1 p.m. ET | Sunday, September 13, 2026
- Venue: Bank of America Stadium (Charlotte, North Carolina)
- Total: 46.5
- Spread: Bears (-3.5)
- Moneyline: Bears (-162), Panthers (+136)
Dunkel Index predictions:
- Over/Under: Under (46.5)
- ATS: Panthers (+3.5)
- Score Prediction: Bears 24, Panthers 23
New Orleans Saints (0-0) at Detroit Lions (0-0)
- Game Time: 1 p.m. ET | Sunday, September 13, 2026
- Venue: Ford Field (Detroit, Michigan)
- Total: 50.5
- Spread: Lions (-7)
- Moneyline: Lions (-310), Saints (+250)
Dunkel Index predictions:
- Over/Under: Under (50.5)
- ATS: Lions (-7)
- Score Prediction: Lions 28, Saints 19
New York Jets (0-0) at Tennessee Titans (0-0)
- Game Time: 1 p.m. ET | Sunday, September 13, 2026
- Venue: Nissan Stadium (Nashville, Tennessee)
- Total: 39.5
- Spread: Titans (-1.5)
- Moneyline: Titans (-122), Jets (+102)
Dunkel Index predictions:
- Over/Under: Over (39.5)
- ATS: Titans (-1.5)
- Score Prediction: Titans 27, Jets 19
Cleveland Browns (0-0) at Jacksonville Jaguars (0-0)
- Game Time: 1 p.m. ET | Sunday, September 13, 2026
- Venue: EverBank Stadium (Jacksonville, Florida)
- Total: 40.5
- Spread: Jaguars (-9.5)
- Moneyline: Jaguars (-469), Browns (+360)
Dunkel Index predictions:
- Over/Under: Over (40.5)
- ATS: Jaguars (-9.5)
- Score Prediction: Jaguars 33, Browns 11
Buffalo Bills (0-0) at Houston Texans (0-0)
- Game Time: 1 p.m. ET | Sunday, September 13, 2026
- Venue: NRG Stadium (Houston, Texas)
- Total: 45.5
- Spread: Bills (-1.5)
- Moneyline: Bills (-118), Texans (-102)
Dunkel Index predictions:
- Over/Under: Over (45.5)
- ATS: Texans (+1.5)
- Score Prediction: Texans 26, Bills 20
Miami Dolphins (0-0) at Las Vegas Raiders (0-0)
- Game Time: 4:25 p.m. ET | Sunday, September 13, 2026
- Venue: Allegiant Stadium (Paradise, Nevada)
- Total: 40.5
- Spread: Raiders (-3.5)
- Moneyline: Raiders (-185), Dolphins (+154)
Dunkel Index predictions:
- Over/Under: Over (40.5)
- ATS: Dolphins (+3.5)
- Score Prediction: Dolphins 23, Raiders 19
Green Bay Packers (0-0) at Minnesota Vikings (0-0)
- Game Time: 4:25 p.m. ET | Sunday, September 13, 2026
- Venue: U.S. Bank Stadium (Minneapolis, Minnesota)
- Total: 46.5
- Spread: Vikings (-1.5)
- Moneyline: Vikings (-122), Packers (+102)
Dunkel Index predictions:
- Over/Under: Under (46.5)
- ATS: Vikings (-1.5)
- Score Prediction: Vikings 23, Packers 19
Arizona Cardinals (0-0) at Los Angeles Chargers (0-0)
- Game Time: 4:25 p.m. ET | Sunday, September 13, 2026
- Venue: SoFi Stadium (Inglewood, California)
- Total: 47.5
- Spread: Chargers (-9.5)
- Moneyline: Chargers (-521), Cardinals (+390)
Dunkel Index predictions:
- Over/Under: Under (47.5)
- ATS: Chargers (-9.5)
- Score Prediction: Chargers 28, Cardinals 17
Washington Commanders (0-0) at Philadelphia Eagles (0-0)
- Game Time: 4:25 p.m. ET | Sunday, September 13, 2026
- Venue: Lincoln Financial Field (Philadelphia, Pennsylvania)
- Total: 44.5
- Spread: Eagles (-4.5)
- Moneyline: Eagles (-218), Commanders (+180)
Dunkel Index predictions:
- Over/Under: Over (44.5)
- ATS: Eagles (-4.5)
- Score Prediction: Eagles 30, Commanders 15
Dallas Cowboys (0-0) at New York Giants (0-0)
- Game Time: 8:20 p.m. ET | Sunday, September 13, 2026
- Venue: MetLife Stadium (East Rutherford, New Jersey)
- Total: 48.5
- Spread: Cowboys (-3)
- Moneyline: Cowboys (-162), Giants (+136)
Dunkel Index predictions:
- Over/Under: Over (48.5)
- ATS: Giants (+3)
- Score Prediction: Giants 29, Cowboys 24
Denver Broncos (0-0) at Kansas City Chiefs (0-0)
- Game Time: 8:15 p.m. ET | Monday, September 14, 2026
- Venue: GEHA Field at Arrowhead Stadium (Kansas City, Missouri)
- Total: 43.5
- Spread: Chiefs (-2.5)
- Moneyline: Chiefs (-155), Broncos (+130)
Dunkel Index predictions:
- Over/Under: Under (43.5)
- ATS: Broncos (+2.5)
- Score Prediction: Broncos 23, Chiefs 18
