Giants vs. Cardinals Dunkel MLB Picks, Predictions and Prop Bets - Sept. 8

The San Francisco Giants host the St. Louis Cardinals at 9:45 p.m. ET on Tuesday. Landen Roupp (8-13, 4.17 ERA) gets the start for the Giants, who are 60-85 this season and fourth in the NL West. Quinn Mathews (1-2, 4.38 ERA) is starting for the Cardinals, who are 72-73 and third in the NL Central.

Per the moneyline, the matchup between the Giants (-111) and Cardinals (-110) looks like a close one. The game has an over/under of 7.5 runs.

Giants vs. Cardinals Odds, Game Time

• Game day: Tuesday, September 8, 2026
• Game time: 9:45 p.m. ET
• Location: San Francisco, California
• Stadium: Oracle Park
• Favorite: Giants (-111)
• Underdog: Cardinals (-110)
• Over/under: 7.5

How to Watch Giants vs. Cardinals

• TV Channel: NBCS-BA and CARD
• Live Stream: Fubo (Watch for free)

Bet now on FanDuel Sportsbook!

Giants vs. Cardinals: Betting the Moneyline

• The Giants have won 24 of the 48 games they were favored on the moneyline this season (50%).
• St. Louis has been pegged as an underdog in 99 games this year and has walked away with the win 47 times (47.5%) in those games.
• San Francisco has a record of 22-22 in games when sportsbooks favor them by at least -111 on the moneyline.
• This season, the Cardinals have been victorious 48 times in 99 chances when named as an underdog of at least -110 or worse on the moneyline.
• The implied moneyline probablility in this matchup gives the Giants a 52.6% chance to win.
• The moneyline set for this matchup implies the Cardinals have a 52.4% chance of walking away with the win.

Giants vs. Cardinals: Betting the Spread & Total

• The Giants have played in 144 games with set over/under, and have combined with opponents to go over the total 68 times (68-65-11).
• Games involving St. Louis have gone over the total set by sportsbooks in 63 of 145 chances this season.
• The Giants have a 71-73-0 record ATS this season (covering 49.3% of the time).
• The Cardinals have posted a record of 81-64-0 against the spread this season.