Saint Louis vs. Loyola Chicago Dunkel Predictions & Vegas Odds - March 4

The No. 25 Saint Louis Billikens (26-3, 14-2 A-10) are favored, by 24.5 points, over the Loyola Chicago Ramblers (7-22, 3-13 A-10) on March 4, 2026 at Chaifetz Arena. The Billikens are 8-2 in their past 10 games, while the Ramblers have gone 2-8 in their past 10. The over/under is set at 155 for the matchup.

In its last time out, Saint Louis won on Saturday 91-76 against Duquesne. Robbie Avila scored a team-high 23 points for Saint Louis in the victory. Loyola Chicago is coming off of a 69-66 victory over Richmond in its most recent outing on Saturday. Miles Rubin scored 19 points in Loyola Chicago's win, leading the team.

Saint Louis vs. Loyola Chicago Odds and Game Time

• When: Wednesday, March 4, 2026 at 8 p.m. ET
• Where: Chaifetz Arena in St. Louis, Missouri
• Spread favorite: Saint Louis -24.5
• Over/Under: 155 points

How to watch Saint Louis vs. Loyola Chicago

• TV Channel: CBS Sports Network
• Check out the rest of our Dunkel Index NCAA Basketball Picks!

Betting the Over/Under: Saint Louis vs. Loyola Chicago

• Saint Louis and its opponents have combined to outscore Wednesday's over/under (155 points) 19 times this season.
• This season, nine games Loyola Chicago has played finished with a combined score higher than 155 points.
• The over/under for the game of 155 is 1.0 point fewer than the combined points per game averages for the Billikens (89.2 points per game) and the Ramblers (66.8 points per game).
• The 145.5 points per game these two teams allow to opponents combined this season are 9.5 less than the 155-point total in this contest.
• This season, the average over/under for Saint Louis' games is 157.9 points, 2.9 more than the total of 155 points set for this contest.
• A difference of 11.4 points separates this matchup's over/under (155 points) and the average over/under in Loyola Chicago's games (143.6) this season.

Betting the Spread: Saint Louis vs. Loyola Chicago

• In Saint Louis' 28 games this season, it has 18 wins against the spread.
• The Billikens have an ATS record of 3-2 in their five games when favored by 24.5 points or more so far this season.
• Loyola Chicago has nine wins against the spread in 29 games this year.
• Saint Louis is 17-0 overall, and 13-4 against the spread, at home.
• As a 24.5-point favorite or greater at home, Saint Louis is 3-2 ATS.
• Away from home, Loyola Chicago is 1-8 overall and 3-6 against the spread.