Duke vs. Notre Dame Dunkel Predictions & Vegas Odds - Feb. 24

The No. 1 Duke Blue Devils (25-2, 13-1 ACC) are favorites, by 17.5 points, versus the Notre Dame Fighting Irish (12-15, 3-11 ACC) on February 24, 2026 at Purcell Pavilion. The Blue Devils have won four in a row, and are 9-1 in their past 10 games, while the Fighting Irish have gone 2-8 in their past 10. The matchup has an over/under set at 139.5 points.

In its last time out, Duke won on Saturday 68-63 over Michigan. Cameron Boozer scored a team-high 18 points for Duke in the win. Notre Dame's most recent outing on Saturday ended in a 73-68 loss to Pittsburgh. Cole Certa scored a team-high 16 points for Notre Dame in the loss.

Duke vs. Notre Dame Odds and Game Time

• When: Tuesday, February 24, 2026 at 7 p.m. ET
• Where: Purcell Pavilion in South Bend, Indiana
• Spread favorite: Duke -17.5
• Moneyline favorite: Duke -3125
• Moneyline underdog: Notre Dame +1250
• Over/Under: 139.5 points

How to watch Duke vs. Notre Dame

• TV Channel: ESPN
• Check out the rest of our Dunkel Index NCAA Basketball Picks!

Betting the Over/Under: Duke vs. Notre Dame

• Duke and its opponents have combined to hit the over on Tuesday's total of 139.5 points 15 times this season.
• A total of 19 of Notre Dame's games have finished with a combined score higher than 139.5 points this season.
• The over/under for the contest of 139.5 is 17.3 points fewer than the combined points per game averages for the Blue Devils (82.4) and Fighting Irish (74.4).
• This matchup's over/under is 3.0 fewer points than the 136.5 these two teams combine to give up per game in 2024.
• Duke has a 145.6 average over/under in its games this season, 6.1 more points than the over/under in this contest.
• Notre Dame's games have an average over/under of 147.8 points this season, 8.3 more points than the over/under for this matchup.

Betting the Spread: Duke vs. Notre Dame

• Duke has played 27 games, with 15 wins against the spread.
• This season, the Blue Devils have an ATS record of 5-6 in their 11 games as a favorite of 17.5 points or more.
• Against the spread, Notre Dame is 14-13-0 this season.
• The Fighting Irish have been underdogs by 17.5 points or more once this season and covered the spread.
• At home this season, Notre Dame is 9-5 overall and 7-7 against the spread.
• At home, as a 17.5-point underdog or more, Notre Dame has one win ATS (1-2).
• Duke is 8-1 overall, and 6-3 against the spread, away from home.
• Duke has one win ATS (1-1) as 17.5-point favorites or more on the road.

Betting the Moneyline: Duke vs. Notre Dame

• Duke has been the moneyline favorite in 23 games this season and won 21 (91.3%) of those contests.
• The Blue Devils are undefeated in six games this season when favored by -3125 or more on the moneyline.
• The moneyline for this contest implies a 96.9% chance of a victory for Duke.
• Notre Dame has come away with three wins in the 16 contests it has been listed as the moneyline underdog this season.
• This is the worst odds of a win that sportsbooks have given the Fighting Irish this season with a +1250 moneyline set for this game.
• The moneyline set for this matchup implies Notre Dame has a 7.4% chance of coming away with a victory in the contest.