Southern Miss vs. Old Dominion Dunkel Predictions & Vegas Odds - Feb. 21

The Southern Miss Golden Eagles (14-14, 7-8 Sun Belt) host the Old Dominion Monarchs (10-18, 6-9 Sun Belt) at Reed Green Coliseum, beginning at 3 p.m. ET on Saturday, February 21, 2026. The Monarchs are 4-point underdogs in the game. The matchup's over/under is set at 147.5.

Southern Miss heads into this game following a 69-65 victory over Troy on Saturday. Tylik Weeks' team-high 32 points led Southern Miss in the victory. In its last outing on Monday, Old Dominion earned an 83-72 victory over Louisiana. Jordan Battle's team-high 27 points paced Old Dominion in the win.

Southern Miss vs. Old Dominion Odds and Game Time

• When: Saturday, February 21, 2026 at 3 p.m. ET
• Where: Reed Green Coliseum in Hattiesburg, Mississippi
• Spread favorite: Southern Miss -4
• Moneyline favorite: Southern Miss -190
• Moneyline underdog: Old Dominion +148
• Over/Under: 147.5 points

How to watch Southern Miss vs. Old Dominion

• TV Channel: ESPN+
• Check out the rest of our Dunkel Index NCAA Basketball Picks!

Betting the Over/Under: Southern Miss vs. Old Dominion

• This season, 13 of Southern Miss' 26 games have gone over Saturday's total of 147.5 points.
• There have been 16 Old Dominion games that ended with a combined score higher than 147.5 points this season.
• The over/under for the matchup of 147.5 is 0.7 points fewer than the combined points per game averages for the Golden Eagles (73.4) and Monarchs (74.8).
• This matchup's total is 2.4 fewer points than the 149.9 these two teams combine to give up per game in 2024.
• On average, the over/under in Southern Miss' games is 0.9 fewer points than the over/under of 147.5 in this contest.
• A difference of 3.9 points separates the average over/under in Old Dominion's games (151.4 points) and this contest's over/under (147.5).

Betting the Spread: Southern Miss vs. Old Dominion

• Southern Miss has 11 wins against the spread in 26 games this year.
• The Golden Eagles have been favored by 4 points or more five times this season and covered the spread in one of them.
• Old Dominion is 15-12-0 against the spread this season.
• The Monarchs have been underdogs by 4 points or more 14 times this year and are 9-5 ATS in those contests.
• At home this season, Southern Miss is 4-6 against the spread and 7-3 overall.
• At home, Southern Miss is winless ATS (0-3) as a 4-point favorite or more.
• This season on the road, Old Dominion is 8-7 against the spread and 3-12 overall.

Betting the Moneyline: Southern Miss vs. Old Dominion

• This season, Southern Miss has won seven out of the eight games in which it has been the moneyline favorite.
• The Golden Eagles have been at least a -190 moneyline favorite five times this season and won each of those games.
• The implied probability of a win from Southern Miss, based on the moneyline, is 65.5%.
• Old Dominion has won in five, or 25%, of the 20 contests it has been named as the moneyline underdog this year.
• This year, the Monarchs have won three of 14 games when listed as at least +148 or worse on the moneyline.
• The moneyline set for this matchup implies Old Dominion has a 40.3% chance of coming away with a victory in the contest.