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Padres vs. Giants Dunkel MLB Picks, Predictions and Prop Bets - Sept. 11

11 September 2026 By Data Skrive

The San Diego Padres bring a four-game win streak into a road matchup versus the San Francisco Giants at 10:15 p.m. ET on Friday. Robbie Ray (11-8, 3.39 ERA) gets the start for the Padres, who are 78-68 this season and second in the NL West. Anthony Molina (3-0, 2.79 ERA) is expected to start for the Giants, who are 62-85 and fourth in the NL West.

Despite playing away from home the Padres are at -149 to win, compared to the Giants at +122. The game's over/under is 8.

Padres vs. Giants Odds, Game Time

  • Game day: Friday, September 11, 2026
  • Game time: 10:15 p.m. ET
  • Location: San Francisco, California
  • Stadium: Oracle Park
  • Favorite: Padres (-149)
  • Underdog: Giants (+122)
  • Over/under: 8

How to Watch Padres vs. Giants

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Padres vs. Giants: Betting the Moneyline

  • The Padres have put together a 40-29 record in games they were favored on the moneyline (winning 58% of those games).
  • San Francisco has been underdogs in 97 games this season and has come away with the win 37 times (38.1%) in those contests.
  • San Diego is 19-6 this season when entering a game favored by -149 or more on the moneyline.
  • This season, the Giants have come away with a win 18 times in 45 chances when named as an underdog of at least +122 or worse on the moneyline.
  • The Padres have a 59.8% chance to win this game based on the moneyline's implied probability.
  • The Giants have an implied victory probability of 45% according to the moneyline set by sportsbooks for this matchup.

Padres vs. Giants: Betting the Spread & Total

  • The Padres have played in 146 games with over/under set, and have combined with opponents to go over the total 64 times (64-77-5).
  • So far this season, San Francisco and its opponents have hit the over in 69 of its 146 games with a total.
  • The Padres have covered 56.2% of their games this season, going 82-64-0 against the spread.
  • The Giants are 73-73-0 against the spread in their 146 games that had a posted line this season.
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