Panthers vs. Sabres NHL Predictions, Picks and Odds - Feb. 27
27 February 2026

Both the Florida Panthers and Buffalo Sabres are coming off a win, heading into their matchup at Amerant Bank Arena on Friday at 7 p.m. ET. Panthers (-115) versus Sabres (-105) appears rather even, according to the moneyline odds.
Florida claimed a 5-1 victory at home its last time out on Feb. 26 against the Toronto Maple Leafs. The Panthers got two points apiece out of three skaters, including Evan Rodrigues (one goal and one assist) and Brad Marchand (two goals).
In its last game on Feb. 25, Buffalo earned a 2-1 road victory against the New Jersey Devils. Tage Thompson (one goal and one assist) and Peyton Krebs (one goal and one assist) each had two points for the Sabres in that outing.
Prepare for this matchup by checking out our prediction for who will come out on top in Friday's hockey action.
Bet now on FanDuel Sportsbook!Panthers vs. Sabres Predictions & Pick
For predictions on the upcoming contest between the Florida Panthers and Buffalo Sabres, computer-calculated moneyline, over/under, and score predictions are below, per Dunkel Index.
- Prediction: Sabres 3 - Panthers 2
- Pick OU:
Under 6.5
(Dunkel projecting 5.05 goals)
Pick with the best in the business! Get free picks for every game, every week at the Dunkel Index.
Panthers vs. Sabres Moneylines
Snag a look below at the latest moneylines for the Panthers-Sabres game.
- Favorite: Panthers (-115)
- Underdog: Sabres (-105)
Panthers Betting Insights
- In the 40 times this season the Panthers have been favored on the moneyline, they have finished 17-23 in those games.
- When playing with moneyline odds of -115 or shorter, Florida has put together a 17-22 record (winning 43.6% of its games).
- Based on the moneyline in this contest, the Panthers' implied win probability is 53.5%.
- In 30 games this season, Florida and its opponent have combined for more than 6.5 goals.
Sabres Betting Insights
- This season the Sabres have won 17 of the 30 games, or 56.7%, in which they've been an underdog.
- This season Buffalo has won 16 of its 29 games, or 55.2%, when it's the underdog by at least -105 on the moneyline.
- The bookmakers' moneyline implies a 51.2% chance of victory for the Sabres.
- Buffalo has combined with its opponent to score more than 6.5 goals in 28 of 58 games this season.
Panthers Key Stats
- Florida ranks 18th in the NHL with 175 goals scored (3.0 per game).
- Defensively, the Panthers are giving up 191 total goals (3.3 per game) to rank 25th in league play.
- Its -16 goal differential ranks 22nd in the league.
- The 41 power-play goals the Panthers have recorded this season are eighth-best in the NHL (on 213 power-play chances).
- Florida has the league's 20th-ranked power-play conversion rate (19.25%).
- The Panthers have capitalized with seven shorthanded goals this season (second among NHL squads).
- Florida's 82.35% penalty-kill success rate is the eighth-best in the league.
- Florida has the 25th-ranked faceoff win rate in the NHL, at 47.7%.
- The Panthers make 10.4% of their shots (24th in the league).
Sabres Key Stats
- Buffalo's 194 goals on the season (3.3 per game) rank 10th in the NHL.
- The Sabres' total of 177 goals conceded (3.0 per game) is 15th in the league.
- With a goal differential of +17, the team is 10th-best in the league in that category.
- With 34 power-play goals (on 172 chances), the Sabres are 16th in the NHL.
- Buffalo scores on 19.77% of its power plays, No. 16 in the league.
- This season, the Sabres have seven shorthanded goals (second in NHL).
- The 82.69% penalty-kill percentage of Buffalo is sixth in the league.
- Buffalo wins 44.6% of faceoffs, 32nd-ranked in the NHL.
- The 12.1% shooting percentage of the Sabres is fifth in the league.
