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Mets vs. Twins Dunkel MLB Picks, Predictions and Prop Bets - April 22

22 April 2026 By Data Skrive

The New York Mets will try to stop a 12-game losing streak when hosting the Minnesota Twins at 7:10 p.m. ET on Wednesday. Clay Holmes (2-2, 1.96 ERA) gets the start for the Mets, who are 7-16 this season and fifth in the NL East. Connor Prielipp (0-0, 0.00 ERA) is starting for the Twins, who are 12-11 and second in the AL Central.

With the Twins (+134) visiting, the Mets (-159) are a solid favorite on the moneyline. The total for the Mets-Twins game is set at 7.5.

Mets vs. Twins Odds, Game Time

  • Game day: Wednesday, April 22, 2026
  • Game time: 7:10 p.m. ET
  • Location: Queens, New York
  • Stadium: Citi Field
  • Favorite: Mets (-159)
  • Underdog: Twins (+134)
  • Over/under: 7.5

How to Watch Mets vs. Twins

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Mets vs. Twins: Betting the Moneyline

  • The Mets have put together a 5-10 record in games they were favored on the moneyline (winning 33.3% of those games).
  • Minnesota has come away with 10 wins in the 16 contests it has been listed as the underdogs in this season.
  • New York has entered seven games this season favored by -159 or more and is 1-6 in those contests.
  • The Twins have a win-loss record of 4-1 when favored by +134 or worse by bookmakers this year.
  • The Mets have an implied moneyline win probability of 61.4% in this matchup.
  • The moneyline set for this matchup implies the Twins have a 42.7% chance of walking away with the win.

Mets vs. Twins: Betting the Spread & Total

  • The Mets have played in 23 games with a set over/under, and have combined with their opponents to go over the total 10 times (10-11-2).
  • Games involving Minnesota have gone over the total set by sportsbooks in 13 of 23 chances this season.
  • The Mets are 8-15-0 ATS this season.
  • The Twins are 13-10-0 against the spread in their 23 games with a line set by sportsbooks this season.
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