Cubs vs. Cardinals Dunkel MLB Picks, Predictions and Prop Bets - July 27

The Chicago Cubs and St. Louis Cardinals square off in the first of a four-game series on Monday at Busch Stadium, at 7:45 p.m. ET. David Peterson (5-7, 5.97 ERA) will start for the Cubs, who are 59-46 this season and second in the NL Central. Matthew Liberatore (5-7, 5.18 ERA) is starting for the Cardinals, who are 53-52 and fourth in the NL Central.

Even though the Cubs are playing on the road at the Cardinals, they are currently favored on the moneyline at -127, compared to the home team at +103. The game has an over/under of 9.5 runs.

Cubs vs. Cardinals Odds, Game Time

• Game day: Monday, July 27, 2026
• Game time: 7:45 p.m. ET
• Location: St. Louis, Missouri
• Stadium: Busch Stadium
• Favorite: Cubs (-127)
• Underdog: Cardinals (+103)
• Over/under: 9.5

How to Watch Cubs vs. Cardinals

• TV Channel: CARD and MARQ
• Live Stream: Fubo (Watch for free)

Bet now on FanDuel Sportsbook!

Cubs vs. Cardinals: Betting the Moneyline

• The Cubs have been the moneyline favorite 72 total times this season. They've finished 40-32 in those games.
• St. Louis has been pegged as an underdog in 73 games this year and has walked away with the win 36 times (49.3%) in those games.
• Chicago has entered 56 games this season favored by -127 or more and is 31-25 in those contests.
• The Cardinals have a win-loss record of 27-25 when favored by +103 or worse by oddsmakers this year.
• Based on this matchup's moneyline, the Cubs' implied win probability is 55.9%.
• The Cardinals have an implied victory probability of 49.3% according to the moneyline set by sportsbooks for this matchup.

Cubs vs. Cardinals: Betting the Spread & Total

• The Cubs have played in 105 games with over/under set, and have combined with opponents to go over the total 56 times (56-47-2).
• St. Louis' games have gone over the total in 39 of its 105 chances.
• The Cubs have collected a 47-58-0 record against the spread this season (covering 44.8% of the time).
• The Cardinals have posted a record of 59-46-0 against the spread this season.