Guardians vs. Twins Dunkel MLB Picks, Predictions and Prop Bets - Sept. 11

The Cleveland Guardians and Minnesota Twins square off in the first of a three-game series on Friday at Target Field, at 8:10 p.m. ET. Parker Messick (11-9, 2.53 ERA) gets the start for the Guardians, who are 74-73 this season and second in the AL Central. Taj Bradley (11-6, 3.95 ERA) is expected to start for the Twins, who are 69-77 and third in the AL Central.

Despite being on the road the Guardians are a moderate moneyline favorite (-123) over the Twins (+101). The contest has a total set at 7.5.

Guardians vs. Twins Odds, Game Time

• Game day: Friday, September 11, 2026
• Game time: 8:10 p.m. ET
• Location: Minneapolis, Minnesota
• Stadium: Target Field
• Favorite: Guardians (-123)
• Underdog: Twins (+101)
• Over/under: 7.5

How to Watch Guardians vs. Twins

• TV Channel: MNNT and CLEG
• Live Stream: Fubo (Watch for free)

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Guardians vs. Twins: Betting the Moneyline

• The Guardians have won 51.6% of the games this season when they were favored on the moneyline (47-44).
• Minnesota has been victorious in 40, or 44%, of the 91 contests it has been chosen as underdogs in this season.
• Cleveland is 36-31 this season when entering a game favored by -123 or more on the moneyline.
• This year, the Twins have won 37 of 79 games when listed as at least +101 or worse on the moneyline.
• The Guardians have an implied moneyline win probability of 55.2% in this matchup.
• Bookmakers have implied with the moneyline set for this matchup that the Twins have a 49.8% chance of pulling out a win.

Guardians vs. Twins: Betting the Spread & Total

• The Guardians have played in 147 games with a set over/under, and have combined with their opponents to go over the total 70 times (70-76-1).
• So far this season, Minnesota and its opponents have hit the over in 80 of its 146 games with a total.
• The Guardians have collected a 69-78-0 record ATS this season.
• The Twins have an against the spread record of 78-68-0 in 146 games with a line this season.