Reds vs. Guardians Dunkel MLB Picks, Predictions and Prop Bets - July 28

The Cincinnati Reds and Cleveland Guardians clash on Tuesday at 1:40 p.m. ET, opening a three-game series at Great American Ball Park. Chase Burns (12-1, 2.42 ERA) will start for the Reds, who are 49-55 this season and fifth in the NL Central. Slade Cecconi (4-7, 4.60 ERA) is starting for the Guardians, who are 54-53 and second in the AL Central.

The Reds are moderate favorites on the moneyline (-164) at home over the Guardians (+134). The total for the Reds-Guardians game is set at 9.

Reds vs. Guardians Odds, Game Time

• Game day: Tuesday, July 28, 2026
• Game time: 1:40 p.m. ET
• Location: Cincinnati, Ohio
• Stadium: Great American Ball Park
• Favorite: Reds (-164)
• Underdog: Guardians (+134)
• Over/under: 9

How to Watch Reds vs. Guardians

• TV Channel: ESPN
• Live Stream: Fubo (Watch for free)

Bet now on FanDuel Sportsbook!

Reds vs. Guardians: Betting the Moneyline

• The Reds have won 17 of the 32 games they were the moneyline favorite this season (53.1%).
• Cleveland has been underdogs in 48 games this season and has come away with the win 24 times (50%) in those contests.
• Cincinnati has a record of 4-2 when favored by -164 or more by bookmakers this season.
• This season, the Guardians have been victorious six times in 11 chances when named as an underdog of at least +134 or longer on the moneyline.
• Based on this contest's moneyline, the Reds' implied win probability is 62.1%.
• Oddsmakers have implied with the moneyline set for this matchup that the Guardians have a 42.7% chance of pulling out a win.

Reds vs. Guardians: Betting the Spread & Total

• In the 104 games in which bookmakers have set an over/under for the Reds, they have combined with opponents to go over the total 56 times (56-47-1).
• Games involving Cleveland have gone over the total set by sportsbooks in 50 of 107 chances this season.
• The Reds have put together a 57-47-0 record against the spread this season.
• The Guardians have posted a record of 53-54-0 against the spread this season.