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White Sox vs. Cardinals Dunkel MLB Picks, Predictions and Prop Bets - Sept. 11

11 September 2026 By Data Skrive

The St. Louis Cardinals hope to end their three-game losing run against the Chicago White Sox, at 8:15 p.m. ET on Friday. Anthony Kay (9-8, 4.53 ERA) will start for the White Sox, who are 75-71 this season and first in the AL Central. Matthew Liberatore (5-14, 5.57 ERA) is the expected starter for the Cardinals, who are 72-75 and fourth in the NL Central.

With moneyline odds of -115 for the White Sox versus -106 for the Cardinals, this game should be a close one. The over/under for the White Sox-Cardinals game is 8.

White Sox vs. Cardinals Odds, Game Time

  • Game day: Friday, September 11, 2026
  • Game time: 8:15 p.m. ET
  • Location: St. Louis, Missouri
  • Stadium: Busch Stadium
  • Favorite: White Sox (-115)
  • Underdog: Cardinals (-106)
  • Over/under: 8

How to Watch White Sox vs. Cardinals

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White Sox vs. Cardinals: Betting the Moneyline

  • The White Sox have been favored on the moneyline 40 total times this season. They've finished 22-18 in those games.
  • St. Louis has been victorious in 47, or 47.5%, of the 99 contests it has been chosen as underdogs in this season.
  • Chicago has entered 35 games this season favored by -115 or more and is 20-15 in those contests.
  • The Cardinals have a mark of 45-46 in contests where bookmakers favor them by -106 or worse on the moneyline.
  • Based on this contest's moneyline, the White Sox's implied win probability is 53.5%.
  • The Cardinals have an implied victory probability of 51.5% according to the moneyline set for this matchup.

White Sox vs. Cardinals: Betting the Spread & Total

  • In the 146 games in which oddsmakers have set an over/under for the White Sox, they have combined with opponents to go over the total 82 times (82-63-1).
  • St. Louis and its opponents have gone over the total this season in 64 of its 147 opportunities.
  • The White Sox have collected an 84-62-0 record against the spread this season.
  • The Cardinals are 81-66-0 against the spread in their 147 games that had a posted line this season.
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