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Dodgers vs. Giants Dunkel MLB Picks, Predictions and Prop Bets - Sept. 21

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21 September 2025 By Data Skrive

The Los Angeles Dodgers have a 3-0 series lead, hoping to sweep the San Francisco Giants on Sunday at Dodger Stadium, at 4:10 p.m. ET. Emmet Sheehan (6-3, 3.17 ERA) will start for the Dodgers, who are 88-67 this season and first in the NL West. Trevor McDonald (0-0, 9.00 ERA) is expected to start for the Giants, who are 76-79 and fourth in the NL West.

At home, the Dodgers are favored to win on the moneyline (-244) over the Giants (+200). The game has an over/under of 8.5 runs.

Dodgers vs. Giants Odds, Game Time

Game day: Sunday, September 21, 2025
Game time: 4:10 p.m. ET
Location: Los Angeles, California
Stadium: Dodger Stadium
Favorite: Dodgers (-244)
Underdog: Giants (+200)
Over/under: 8.5

How to Watch Dodgers vs. Giants

TV Channel: NBC Sports Bay Area
Live Stream: Fubo (Watch for free)

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Dodgers vs. Giants: Betting the Moneyline

The Dodgers have won 57.7% of the games this season when they were the moneyline favorite (79-58).
San Francisco has won in 30, or 44.8%, of the 67 contests it has been named as odds-on underdogs in this year.
Los Angeles is 21-5 this season when entering a game favored by -244 or more on the moneyline.
Oddsmakers have given the Giants the worst odds of winning they have seen this season with a +200 moneyline listed for this contest.
Based on this contest's moneyline, the Dodgers have an implied win probability of 70.9%.
The moneyline set for this matchup implies the Giants have a 33.3% chance of walking away with the win.

Dodgers vs. Giants: Betting the Spread & Total

The Dodgers have played in 155 games with an over/under set, and have combined with their opponents to go over the total 72 times (72-74-9).
San Francisco and its opponents have gone over the total this season in 72 of its 155 opportunities.
The Dodgers have a 68-87-0 record against the spread this season (covering 43.9% of the time).
The Giants are 72-83-0 against the spread in their 155 games that had a posted line this season.

Dunkel Index Prediction for Dodgers vs. Giants

Pick OU: Over (8.5)
Prediction: Dodgers 6 - Giants 4

Check out all the Dunkel Index MLB Baseball Picks!

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About the author

Data Skrive

Data Skrive creates sports articles about every player, on every team, in every league, for every game, for every fan. Data Skrive know sports. With over 100M monthly readers across 500+ websites and 200+ DMAs, their innovative Fan Engagement Solution creates engaging and entertaining sports content that fans value to drive revenue for their customers. Sports never stop, and covering every topic at the right time is not feasible. Data Skrive's technology is able to cover highly relevant topics that are interesting and engaging to your fans.