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NFL Predictions & Betting Odds - Week 18

01 January 2026 By Data Skrive

The Week 18 NFL schedule has plenty of quality competition on the docket. Among those games is the Seattle Seahawks taking on the San Francisco 49ers.

We've got you covered with a quick summary on every NFL contest this week with over/unders, spreads, moneylines, and Dunkel Index predictions. Continue scrolling for the details.

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Week 18 Games, Betting Info, and Predictions

There are 16 games on the NFL schedule this week. Here's a glance at each one:

Carolina Panthers (8-9) at Tampa Bay Buccaneers (8-9)

  • Game Time: 4:30 p.m. ET | Saturday, January 3, 2026
  • Venue: Raymond James Stadium (Tampa, Florida)
  • Total: 43.5
  • Spread: Buccaneers (-3)
  • Moneyline: Buccaneers (-155), Panthers (+130)

Dunkel Index predictions:

  • Over/Under: Over (43.5)
  • ATS: Buccaneers (-3)
  • Score Prediction: Buccaneers 24, Panthers 20

Seattle Seahawks (14-3) at San Francisco 49ers (12-5)

  • Game Time: 8 p.m. ET | Saturday, January 3, 2026
  • Venue: Levi's Stadium (Santa Clara, California)
  • Total: 48.5
  • Spread: Seahawks (-2.5)
  • Moneyline: Seahawks (-148), 49ers (+124)

Dunkel Index predictions:

  • Over/Under: Over (48.5)
  • ATS: 49ers (+2.5)
  • Score Prediction: Seahawks 25, 49ers 23

Dallas Cowboys (7-8-1) at New York Giants (3-13)

  • Game Time: 1 p.m. ET | Sunday, January 4, 2026
  • Venue: MetLife Stadium (East Rutherford, New Jersey)
  • Total: 50.5
  • Spread: Cowboys (-3)
  • Moneyline: Cowboys (-166), Giants (+140)

Dunkel Index predictions:

  • Over/Under: Over (50.5)
  • ATS: Giants (+3)
  • Score Prediction: Giants 28, Cowboys 25

Green Bay Packers (9-6-1) at Minnesota Vikings (8-8)

  • Game Time: 1 p.m. ET | Sunday, January 4, 2026
  • Venue: U.S. Bank Stadium (Minneapolis, Minnesota)
  • Total: 37.5
  • Spread: Vikings (-12.5)
  • Moneyline: Vikings (-649), Packers (+470)

Dunkel Index predictions:

  • Over/Under: Over (37.5)
  • ATS: Packers (+12.5)
  • Score Prediction: Vikings 22, Packers 21

Indianapolis Colts (8-8) at Houston Texans (11-5)

  • Game Time: 1 p.m. ET | Sunday, January 4, 2026
  • Venue: NRG Stadium (Houston, Texas)
  • Total: 38.5
  • Spread: Texans (-9.5)
  • Moneyline: Texans (-535), Colts (+400)

Dunkel Index predictions:

  • Over/Under: Over (38.5)
  • ATS: Texans (-9.5)
  • Score Prediction: Texans 28, Colts 17

Cleveland Browns (4-12) at Cincinnati Bengals (6-10)

  • Game Time: 1 p.m. ET | Sunday, January 4, 2026
  • Venue: Paycor Stadium (Cincinnati, Ohio)
  • Total: 47.5
  • Spread: Bengals (-8.5)
  • Moneyline: Bengals (-455), Browns (+350)

Dunkel Index predictions:

  • Over/Under: Under (47.5)
  • ATS: Bengals (-8.5)
  • Score Prediction: Bengals 28, Browns 19

New Orleans Saints (6-10) at Atlanta Falcons (7-9)

  • Game Time: 1 p.m. ET | Sunday, January 4, 2026
  • Venue: Mercedes-Benz Stadium (Atlanta, Georgia)
  • Total: 43.5
  • Spread: Falcons (-4.5)
  • Moneyline: Falcons (-205), Saints (+170)

Dunkel Index predictions:

  • Over/Under: Under (43.5)
  • ATS: Falcons (-4.5)
  • Score Prediction: Falcons 24, Saints 19

Tennessee Titans (3-13) at Jacksonville Jaguars (12-4)

  • Game Time: 1 p.m. ET | Sunday, January 4, 2026
  • Venue: EverBank Stadium (Jacksonville, Florida)
  • Total: 46.5
  • Spread: Jaguars (-12.5)
  • Moneyline: Jaguars (-752), Titans (+525)

Dunkel Index predictions:

  • Over/Under: Under (46.5)
  • ATS: Jaguars (-12.5)
  • Score Prediction: Jaguars 34, Titans 12

Los Angeles Chargers (11-5) at Denver Broncos (13-3)

  • Game Time: 4:25 p.m. ET | Sunday, January 4, 2026
  • Venue: Empower Field at Mile High (Denver, Colorado)
  • Total: 38.5
  • Spread: Broncos (-14.5)
  • Moneyline: Broncos (-1587), Chargers (+900)

Dunkel Index predictions:

  • Over/Under: Over (38.5)
  • ATS: Chargers (+14.5)
  • Score Prediction: Broncos 24, Chargers 19

Detroit Lions (8-8) at Chicago Bears (11-5)

  • Game Time: 4:25 p.m. ET | Sunday, January 4, 2026
  • Venue: Soldier Field (Chicago, Illinois)
  • Total: 51.5
  • Spread: Bears (-3.5)
  • Moneyline: Bears (-198), Lions (+164)

Dunkel Index predictions:

  • Over/Under: Over (51.5)
  • ATS: Bears (-3.5)
  • Score Prediction: Bears 28, Lions 24

Miami Dolphins (7-9) at New England Patriots (13-3)

  • Game Time: 4:25 p.m. ET | Sunday, January 4, 2026
  • Venue: Gillette Stadium (Foxborough, Massachusetts)
  • Total: 44.5
  • Spread: Patriots (-13.5)
  • Moneyline: Patriots (-1000), Dolphins (+650)

Dunkel Index predictions:

  • Over/Under: Over (44.5)
  • ATS: Patriots (-13.5)
  • Score Prediction: Patriots 31, Dolphins 15

New York Jets (3-13) at Buffalo Bills (11-5)

  • Game Time: 4:25 p.m. ET | Sunday, January 4, 2026
  • Venue: Highmark Stadium (Orchard Park, New York)
  • Total: 39.5
  • Spread: Bills (-12.5)
  • Moneyline: Bills (-800), Jets (+550)

Dunkel Index predictions:

  • Over/Under: Over (39.5)
  • ATS: Bills (-12.5)
  • Score Prediction: Bills 36, Jets 13

Kansas City Chiefs (6-10) at Las Vegas Raiders (2-14)

  • Game Time: 4:25 p.m. ET | Sunday, January 4, 2026
  • Venue: Allegiant Stadium (Paradise, Nevada)
  • Total: 36.5
  • Spread: Chiefs (-3.5)
  • Moneyline: Chiefs (-225), Raiders (+185)

Dunkel Index predictions:

  • Over/Under: Over (36.5)
  • ATS: Chiefs (-3.5)
  • Score Prediction: Chiefs 26, Raiders 15

Washington Commanders (4-12) at Philadelphia Eagles (11-5)

  • Game Time: 4:25 p.m. ET | Sunday, January 4, 2026
  • Venue: Lincoln Financial Field (Philadelphia, Pennsylvania)
  • Total: 38.5
  • Spread: Eagles (-3)
  • Moneyline: Eagles (-180), Commanders (+150)

Dunkel Index predictions:

  • Over/Under: Over (38.5)
  • ATS: Eagles (-3)
  • Score Prediction: Eagles 31, Commanders 13

Arizona Cardinals (3-13) at Los Angeles Rams (11-5)

  • Game Time: 4:25 p.m. ET | Sunday, January 4, 2026
  • Venue: SoFi Stadium (Inglewood, California)
  • Total: 48.5
  • Spread: Rams (-14.5)
  • Moneyline: Rams (-1205), Cardinals (+750)

Dunkel Index predictions:

  • Over/Under: Over (48.5)
  • ATS: Rams (-14.5)
  • Score Prediction: Rams 38, Cardinals 12

Baltimore Ravens (8-8) at Pittsburgh Steelers (9-7)

  • Game Time: 8:20 p.m. ET | Sunday, January 4, 2026
  • Venue: Acrisure Stadium (Pittsburgh, Pennsylvania)
  • Total: 41.5
  • Spread: Ravens (-3.5)
  • Moneyline: Ravens (-192), Steelers (+160)

Dunkel Index predictions:

  • Over/Under: Over (41.5)
  • ATS: Steelers (+3.5)
  • Score Prediction: Steelers 24, Ravens 23

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