Cardinals vs. Royals Dunkel MLB Picks, Predictions and Prop Bets - May 15

The St. Louis Cardinals host the Kansas City Royals to open a three-game series at Busch Stadium, with first pitch at 8:15 p.m. ET on Friday. Dustin May (3-4, 4.85 ERA) gets the start for the Cardinals, who are 25-18 this season and third in the NL Central. Michael Wacha (4-2, 2.63 ERA) is starting for the Royals, who are 19-25 and fifth in the AL Central.

The moneyline odds for the game between the Cardinals (-112) and Royals (-107) suggest a close contest. The contest has an over/under set at 8.5.

Cardinals vs. Royals Odds, Game Time

• Game day: Friday, May 15, 2026
• Game time: 8:15 p.m. ET
• Location: St. Louis, Missouri
• Stadium: Busch Stadium
• Favorite: Cardinals (-112)
• Underdog: Royals (-107)
• Over/under: 8.5

How to Watch Cardinals vs. Royals

• TV Channel: CARD and ROYL
• Live Stream: Fubo (Watch for free)

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Cardinals vs. Royals: Betting the Moneyline

• The Cardinals have won two of the four games they were listed as the moneyline favorite this season (50%).
• Kansas City has been victorious in seven, or 36.8%, of the 19 contests it has been chosen as underdogs in this season.
• St. Louis has played as favorites of -112 or more twice this season and split those games.
• The Royals have a win-loss record of 7-12 when favored by -107 or worse by oddsmakers this year.
• Based on this matchup's moneyline, the Cardinals have an implied win probability of 52.8%.
• The Royals have an implied victory probability of 51.7% according to the moneyline set for this matchup.

Cardinals vs. Royals: Betting the Spread & Total

• The Cardinals have had an over/under set by bookmakers 43 times, and have combined with opponents to go over the total in 17 of those games (17-21-5).
• Kansas City's games have gone over the total in 20 of its 44 chances.
• The Cardinals have collected a 27-16-0 record against the spread this season (covering 62.8% of the time).
• The Royals are 18-26-0 against the spread in their 44 games that had a posted line this season.