Saints vs. Panthers Week 10 Dunkel NFL Picks, Predictions and Odds

The New Orleans Saints (3-5) are slight favorites (-1.5) over the Carolina Panthers (3-5). The Panthers have lost three games in a row. The over/under for this one is set at 48.5 points.

With 370.5 yards allowed per game on defense, which ranks fourth-worst in the NFL, the Saints have been forced to lean on their 19th-ranked offense (325.8 yards per contest) to keep them competitive. The Panthers' defense has been a bottom-five unit in scoring defense this season, conceding 27.4 points per game, which ranks fifth-worst in the NFL. Offensively, they rank 11th with 24.9 points per contest.

Saints vs. Panthers Odds and Game Time

• Date: Sunday, November 15, 2026
• Time: 1 p.m. ET
• City: New Orleans, Louisiana
• Venue: Caesars Superdome
• Total: 48.5 points
• Spread: Saints -1.5
• Moneyline: Saints (-122), Panthers (+102)

How to watch Saints vs. Panthers

• TV Channel: FOX

Betting the Over/Under: Saints vs. Panthers

• In four of eight games this season, the Saints and their opponents have combined to total more than 48.5 points.
• New Orleans games have hit the over five out of eight times this season.
• The Panthers have played three games this season that have had more than 48.5 combined points scored.
• Carolina games have gone over the point total four out of eight times this season.
• These two teams are scoring 48 points per game between them, 0.5 fewer than this matchup's total.
• Opponents of these two teams average 54.4 points per game combined, 5.9 more points than this matchup's total.

Betting the Spread: Saints vs. Panthers

• New Orleans has compiled a 3-5-0 ATS record so far this year.
• New Orleans has not covered the spread this season (0-3 ATS) when playing as at least 1.5-point favorites.
• The Panthers have covered three times in eight matchups with a spread this season.
• Carolina has been an underdog by 1.5 points or more four times this season, and covered the spread in one of those games.
• The Saints have not covered the spread at home, and are 1-4 overall there this season.
• New Orleans is winless ATS (0-3) as 1.5-point favorites or greater at home.
• The Panthers are 2-2 overall with two wins against the spread on the road.
• Carolina is winless ATS (0-1) away from home as 1.5-point underdogs or more.

Betting the Moneyline: Saints vs. Panthers

• New Orleans has won 33.3% of the games this season when it was the moneyline favorite (1-2).
• The Panthers have entered the game as underdogs four times this season and won once.
• New Orleans has played as a moneyline favorite of -122 or shorter in just two games this season, and it split 1-1.
• Carolina is 1-3 this season when entering a game as the underdog by +102 or more on the moneyline.
• Based on this game's moneyline, the Saints' implied win probability is 55.0%.

Dunkel Prediction for Saints vs. Panthers

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