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NFL Predictions & Betting Odds - Week 10

10 November 2026 By Data Skrive

The Pittsburgh Steelers and the Cincinnati Bengals hit the field for one of many exciting matchups on the NFL slate in Week 10.

We've got you covered with a quick rundown on every NFL contest this week with over/unders, spreads, moneylines, and Dunkel Index predictions. Keep reading for the key information.

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Week 10 Games, Betting Info, and Predictions

There are 14 games on the pro football docket this week. Below is a peek at each one:

Washington Commanders (2-5-1) at New York Giants (5-2-1)

  • Game Time: 8:15 p.m. ET | Thursday, November 12, 2026
  • Venue: MetLife Stadium (East Rutherford, New Jersey)
  • Total: 42.5
  • Spread: Giants (-2.5)
  • Moneyline: Giants (-135), Commanders (+114)

Dunkel Index predictions:

  • Over/Under: Over (42.5)
  • ATS: Giants (-2.5)
  • Score Prediction: Giants 27, Commanders 19

New England Patriots (5-4) at Detroit Lions (6-2)

  • Game Time: 9:30 a.m. ET | Sunday, November 15, 2026
  • Venue: Allianz Arena (Munich, Germany)
  • Total: 51.5
  • Spread: Lions (-2.5)
  • Moneyline: Lions (-148), Patriots (+124)

Dunkel Index predictions:

  • Over/Under: Under (51.5)
  • ATS: Patriots (+2.5)
  • Score Prediction: Lions 25, Patriots 24

Minnesota Vikings (6-2) at Green Bay Packers (6-3)

  • Game Time: 1 p.m. ET | Sunday, November 15, 2026
  • Venue: Lambeau Field (Green Bay, Wisconsin)
  • Total: 41.5
  • Spread: Packers (-4.5)
  • Moneyline: Packers (-218), Vikings (+180)

Dunkel Index predictions:

  • Over/Under: Under (41.5)
  • ATS: Vikings (+4.5)
  • Score Prediction: Packers 21, Vikings 18

Houston Texans (3-5) at Cleveland Browns (5-4)

  • Game Time: 1 p.m. ET | Sunday, November 15, 2026
  • Venue: Huntington Bank Field (Cleveland, Ohio)
  • Total: 39.5
  • Spread: Texans (-4.5)
  • Moneyline: Texans (-225), Browns (+185)

Dunkel Index predictions:

  • Over/Under: Over (39.5)
  • ATS: Browns (+4.5)
  • Score Prediction: Browns 23, Texans 22

Kansas City Chiefs (6-2) at Atlanta Falcons (3-6)

  • Game Time: 1 p.m. ET | Sunday, November 15, 2026
  • Venue: Mercedes-Benz Stadium (Atlanta, Georgia)
  • Total: 45.5
  • Spread: Chiefs (-3.5)
  • Moneyline: Chiefs (-180), Falcons (+150)

Dunkel Index predictions:

  • Over/Under: Under (45.5)
  • ATS: Falcons (+3.5)
  • Score Prediction: Chiefs 23, Falcons 21

Miami Dolphins (1-7) at Indianapolis Colts (2-7)

  • Game Time: 1 p.m. ET | Sunday, November 15, 2026
  • Venue: Lucas Oil Stadium (Indianapolis, Indiana)
  • Total: 40.5
  • Spread: Colts (-2.5)
  • Moneyline: Colts (-135), Dolphins (+114)

Dunkel Index predictions:

  • Over/Under: Over (40.5)
  • ATS: Colts (-2.5)
  • Score Prediction: Colts 24, Dolphins 20

Carolina Panthers (3-5) at New Orleans Saints (3-5)

  • Game Time: 1 p.m. ET | Sunday, November 15, 2026
  • Venue: Caesars Superdome (New Orleans, Louisiana)
  • Total: 47.5
  • Spread: Saints (-1.5)
  • Moneyline: Saints (-122), Panthers (+102)

Dunkel Index predictions:

  • Over/Under: Over (47.5)
  • ATS: Panthers (+1.5)
  • Score Prediction: Saints 26, Panthers 25

Buffalo Bills (7-1) at New York Jets (2-7)

  • Game Time: 1 p.m. ET | Sunday, November 15, 2026
  • Venue: MetLife Stadium (East Rutherford, New Jersey)
  • Total: 50.5
  • Spread: Bills (-8.5)
  • Moneyline: Bills (-549), Jets (+410)

Dunkel Index predictions:

  • Over/Under: Under (50.5)
  • ATS: Bills (-8.5)
  • Score Prediction: Bills 31, Jets 19

Jacksonville Jaguars (6-2) at Tennessee Titans (1-7)

  • Game Time: 1 p.m. ET | Sunday, November 15, 2026
  • Venue: Nissan Stadium (Nashville, Tennessee)
  • Total: 46.5
  • Spread: Jaguars (-10.5)
  • Moneyline: Jaguars (-549), Titans (+410)

Dunkel Index predictions:

  • Over/Under: Under (46.5)
  • ATS: Jaguars (-10.5)
  • Score Prediction: Jaguars 31, Titans 12

Los Angeles Rams (5-4) at Arizona Cardinals (3-6)

  • Game Time: 4:05 p.m. ET | Sunday, November 15, 2026
  • Venue: State Farm Stadium (Glendale, Arizona)
  • Total: 40.5
  • Spread: Rams (-9.5)
  • Moneyline: Rams (-441), Cardinals (+340)

Dunkel Index predictions:

  • Over/Under: Over (40.5)
  • ATS: Cardinals (+9.5)
  • Score Prediction: Rams 25, Cardinals 21

Seattle Seahawks (5-4) at Las Vegas Raiders (4-5)

  • Game Time: 4:05 p.m. ET | Sunday, November 15, 2026
  • Venue: Allegiant Stadium (Paradise, Nevada)
  • Total: 43.5
  • Spread: Seahawks (-3.5)
  • Moneyline: Seahawks (-180), Raiders (+150)

Dunkel Index predictions:

  • Over/Under: Over (43.5)
  • ATS: Seahawks (-3.5)
  • Score Prediction: Seahawks 27, Raiders 22

San Francisco 49ers (7-1) at Dallas Cowboys (4-5)

  • Game Time: 4:25 p.m. ET | Sunday, November 15, 2026
  • Venue: AT&T Stadium (Arlington, Texas)
  • Total: 55.5
  • Spread: 49ers (-3.5)
  • Moneyline: 49ers (-205), Cowboys (+170)

Dunkel Index predictions:

  • Over/Under: Under (55.5)
  • ATS: 49ers (-3.5)
  • Score Prediction: 49ers 29, Cowboys 22

Pittsburgh Steelers (6-2) at Cincinnati Bengals (6-2)

  • Game Time: 8:20 p.m. ET | Sunday, November 15, 2026
  • Venue: Paycor Stadium (Cincinnati, Ohio)
  • Total: 48.5
  • Spread: Bengals (-3.5)
  • Moneyline: Bengals (-180), Steelers (+150)

Dunkel Index predictions:

  • Over/Under: Under (48.5)
  • ATS: Bengals (-3.5)
  • Score Prediction: Bengals 26, Steelers 21

Los Angeles Chargers (0-8) at Baltimore Ravens (4-5)

  • Game Time: 8:15 p.m. ET | Monday, November 16, 2026
  • Venue: M&T Bank Stadium (Baltimore, Maryland)
  • Total: 38.5
  • Spread: Ravens (-5.5)
  • Moneyline: Ravens (-225), Chargers (+185)

Dunkel Index predictions:

  • Over/Under: Over (38.5)
  • ATS: Ravens (-5.5)
  • Score Prediction: Ravens 27, Chargers 17

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