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Pirates vs. Cardinals Dunkel MLB Picks, Predictions and Prop Bets - April 27

27 April 2026 By Data Skrive

The St. Louis Cardinals take a four-game losing streak into a home contest versus the Pittsburgh Pirates, at 6:40 p.m. ET on Monday. Mason Montgomery (1-0, 3.97 ERA) gets the start for the Pirates, who are 16-12 this season and third in the NL Central. Dustin May (3-2, 5.84 ERA) is the expected starter for the Cardinals, who are 14-13 and fifth in the NL Central.

The Cardinals (+114) are on the road versus the favored Pirates (-135). The total in this contest is set at 8.

Pirates vs. Cardinals Odds, Game Time

  • Game day: Monday, April 27, 2026
  • Game time: 6:40 p.m. ET
  • Location: Pittsburgh, Pennsylvania
  • Stadium: PNC Park
  • Favorite: Pirates (-135)
  • Underdog: Cardinals (+114)
  • Over/under: 8

How to Watch Pirates vs. Cardinals

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Pirates vs. Cardinals: Betting the Moneyline

  • The Pirates have put together an 11-4 record in games they were favored on the moneyline (winning 73.3% of those games).
  • St. Louis has come away with 12 wins in the 24 contests it has been listed as the underdogs in this season.
  • Pittsburgh has a record of 4-4 in games when oddsmakers favor them by at least -135 on the moneyline.
  • This season, the Cardinals have come away with a win six times in 14 chances when named as an underdog of at least +114 or longer on the moneyline.
  • Based on this game's moneyline, the Pirates have an implied win probability of 57.4%.
  • The Cardinals have an implied victory probability of 46.7% according to the moneyline set by oddsmakers for this matchup.

Pirates vs. Cardinals: Betting the Spread & Total

  • The Pirates have combined with opponents to hit the over on the total 15 times this season for a 15-13-0 record against the over/under.
  • St. Louis' games have gone over the total in 13 of its 27 chances.
  • The Pirates have put together a 17-11-0 record ATS this season.
  • The Cardinals have posted a record of 15-12-0 against the spread this season.
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