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Yankees vs. Orioles Dunkel MLB Picks, Predictions and Prop Bets - Sept. 21

21 September 2025 By Data Skrive

The New York Yankees and Baltimore Orioles meet on Sunday at 1:35 p.m. ET. Cam Schlittler (3-3, 3.41 ERA) will start for the Yankees, who are 87-68 this season and second in the AL East. Kyle Bradish (1-1, 2.45 ERA) is starting for the Orioles, who are 73-82 and fifth in the AL East.

Despite playing away from home the Yankees are at -132 to win, compared to the Orioles at +112. The total for this contest is set at 8.5.

Yankees vs. Orioles Odds, Game Time

  • Game day: Sunday, September 21, 2025
  • Game time: 1:35 p.m. ET
  • Location: Baltimore, Maryland
  • Stadium: Oriole Park at Camden Yards
  • Favorite: Yankees (-132)
  • Underdog: Orioles (+112)
  • Over/under: 8.5

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Yankees vs. Orioles: Betting the Moneyline

  • The Yankees have won 77 of the 132 games they were the moneyline favorite this season (58.3%).
  • Baltimore has been pegged as an underdog in 88 games this year and has walked away with the win 40 times (45.5%) in those games.
  • New York has a record of 67-43 in games when sportsbooks favor them by at least -132 on the moneyline.
  • This season, the Orioles have been victorious 21 times in 52 chances when named as an underdog of at least +112 or worse on the moneyline.
  • The Yankees have a 56.9% chance to win this game based on the moneyline's implied probability.
  • The moneyline set for this matchup implies the Orioles have a 47.2% chance of walking away with the win.

Yankees vs. Orioles: Betting the Spread & Total

  • The Yankees have combined with opponents to go over the total 74 times this season for a 74-74-6 record against the over/under.
  • Baltimore and its opponents have gone over the total this season in 63 of its 155 opportunities.
  • The Yankees have covered 46.1% of their games this season, going 71-83-0 against the spread.
  • The Orioles are 74-81-0 against the spread in their 155 games with a line set by sportsbooks this season.

Dunkel Index Prediction for Yankees vs. Orioles

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