Bills vs. Dolphins Week 10 Dunkel NFL Picks, Predictions and Odds

In a battle of two division rivals, the Buffalo Bills (6-2) will meet the Miami Dolphins (2-7). The Bills are solid favorites, expected to win by at least a touchdown (currently -9.5). The expected point total for the game is 50.5.

The Bills rank 12th in total defense this year (311.3 yards allowed per game), but they've been thriving on the offensive side of the ball, ranking best in the NFL with 385.5 total yards per game. From an offensive perspective, the Dolphins are generating 20 points per game (26th-ranked). They rank 24th in the NFL on defense (27 points given up per game).

Bills vs. Dolphins Odds and Game Time

• Date: Sunday, November 9, 2025
• Time: 1 p.m. ET
• City: Miami Gardens, Florida
• Venue: Hard Rock Stadium
• Total: 50.5 points
• Spread: Bills -9.5
• Moneyline: Bills (-549), Dolphins (+410)

How to watch Bills vs. Dolphins

• TV Channel: CBS (WROC-Rochester, NY)
• Live Stream: Fubo

Betting the Over/Under: Bills vs. Dolphins

• In two games this season, the Bills and their opponents have combined to total more than 50.5 points.
• In Buffalo's eight games this season, the combined scoring has gone over the point total four times.
• The Dolphins have combined with their opponents to score more than 50.5 points in four of nine games this season.
• Miami and its opponent have combined to hit the over six out of nine times this season.
• The two teams combine to score 49.4 points per game, 1.1 fewer points than this matchup's over/under.
• These two teams surrender a combined 47.9 points per game, 2.6 fewer points than this matchup's over/under.

Betting the Spread: Bills vs. Dolphins

• Buffalo has compiled a 4-4-0 ATS record so far this year.
• Buffalo has not covered the spread when favored by 9.5 points or more this season (in two opportunities).
• The Dolphins are 4-5-0 ATS this year.
• Miami has covered the spread when playing as at least 9.5-point underdogs in its only opportunity this season.
• At home this season, the Dolphins have two wins against the spread and are 1-3 overall.
• The Bills have two wins against the spread and are 2-1 overall, on the road.

Betting the Moneyline: Bills vs. Dolphins

• Buffalo has a 4-2 record in games they were favored on the moneyline (winning 66.7% of those games).
• The Dolphins have entered the game as underdogs six times this season and won once.
• Buffalo has played as a moneyline favorite of -549 or shorter in just two games this season, and it won both.
• Miami has played as an underdog of +410 or more once this season and lost that game.
• The Bills have an 84.6% chance to win this game based on the moneyline's implied probability.

Dunkel Prediction for Bills vs. Dolphins

For more expert NFL picks, visit our Dunkel Index NFL Picks and Predictions.