Bills vs. Dolphins Week 10 Dunkel NFL Picks, Predictions and Odds

In a matchup of two division rivals, the Buffalo Bills (6-2) will play the Miami Dolphins (2-7). The Bills are solid favorites, expected to win by at least a touchdown (currently -9.5). The expected point total for the game is 50.5.

The Bills sport the 12th-ranked defense this year (311.3 yards allowed per game), and they've been more effective offensively, ranking best with 385.5 yards per game. In terms of points scored the Dolphins rank 26th in the NFL (20 points per game), and they are 24th on defense (27 points allowed per game).

Bills vs. Dolphins Odds and Game Time

• Date: Sunday, November 9, 2025
• Time: 1 p.m. ET
• City: Miami Gardens, Florida
• Venue: Hard Rock Stadium
• Total: 50.5 points
• Spread: Bills -9.5
• Moneyline: Bills (-469), Dolphins (+360)

How to watch Bills vs. Dolphins

• TV Channel: CBS (WROC-Rochester, NY)
• Live Stream: Fubo

Betting the Over/Under: Bills vs. Dolphins

• The Bills and their opponents have scored a combined total of more than 50.5 points twice this season (in eight games).
• Buffalo games have gone over the point total four out of eight times this season.
• Dolphins games this season have had a combined scoring total higher than 50.5 points in four of nine outings.
• In 2025, six Miami games have hit the over.
• The teams combine to score 49.4 points per game, 1.1 fewer points than this matchup's over/under.
• These two teams allow a combined 47.9 points per game, 2.6 fewer points than this contest's total.

Betting the Spread: Bills vs. Dolphins

• Buffalo has compiled a 4-4-0 record against the spread this season.
• Buffalo has not covered the spread when favored by 9.5 points or more this season (in two opportunities).
• The Dolphins have won four games against the spread this year, failing to cover five times.
• Miami has won its only game this season when playing as at least 9.5-point underdogs.
• The Dolphins have two wins against the spread, and are 1-3 overall, at home this year.
• In away games, the Bills have two wins against the spread and are 2-1 overall.

Betting the Moneyline: Bills vs. Dolphins

• Buffalo has won 66.7% of the games this season when it was the moneyline favorite (4-2).
• The Dolphins have been underdogs in six games this season and won one (16.7%) of those contests.
• Buffalo has played as a moneyline favorite of -469 or shorter in just two games this season, and it won both.
• Miami has played as an underdog of +360 or more once this season and lost that game.
• Based on this matchup's moneyline, the Bills' implied win probability is 82.4%.

Dunkel Prediction for Bills vs. Dolphins

For more expert NFL picks, visit our Dunkel Index NFL Picks and Predictions.