Oregon vs. Iowa Dunkel NCAA Football Picks, Predictions and Odds - Nov. 8

The No. 6 Oregon Ducks (7-1) and the ninth-ranked run offense will take the field against the Iowa Hawkeyes (6-2) and the 10th-ranked rush defense on Saturday, November 8, 2025. The Ducks are favored by 6.5 points in the game.

The Ducks won against the Wisconsin Badgers in their most recent game, 21-7.

The Hawkeyes' last contest was versus the Minnesota Golden Gophers, and they won by a score of 41-3.

Oregon vs. Iowa Predictions

Ahead of the upcoming contest between the Oregon Ducks and Iowa Hawkeyes, computer-derived against-the-spread, over/under, and score predictions are below, sourced from Dunkel Index.

• Pick ATS: Hawkeyes (+ 6.5)
• Pick OU: Under (40.5)
  
• Prediction: Ducks 20 - Hawkeyes 17

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Oregon vs. Iowa Moneylines

Grab a peek below at the latest moneylines for the Ducks-Hawkeyes matchup.

• Oregon Moneyline: -244
• Iowa Moneyline: +200

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Oregon Betting Insights

• Oregon has been the moneyline favorite six total times this season. It has gone 5-1 in those games.
• When it has played as a moneyline favorite with odds of -244 or shorter, Oregon has a 5-1 record (winning 83.3% of its games).
• Ducks games this season have featured more combined points than this contest's total of 40.5 points seven times.
• Ducks contests this year have an average point total of 53.8, 13.3 more points than this matchup's over/under.
• The Hawkeyes are college football's 65th-highest scoring team this season compared to the 10th-ranked Ducks.

Iowa Betting Insights

• Iowa has lost both games it has played as underdogs this season.
• Iowa has played as an underdog of +200 or more once this season and lost that game.
• Iowa and its opponents have combined to score more than 40.5 points in five of eight games this season.
• Iowa's average game total this season has been 43.6, 3.1 more points than this matchup's over/under.

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Key Stats for Oregon vs. Iowa

• The Ducks have been a tough matchup for opposing teams, as they rank top-25 in both total offense (ninth-best with 483.9 yards per game) and total defense (fourth-best with 239.4 yards allowed per game) this year.
• Oregon has been surging on both sides of the ball, ranking fifth-best in scoring offense (41.3 points per game) and sixth-best in scoring defense (13.5 points allowed per game).
• While the Hawkeyes' offense has been stuck in neutral, ranking 16th-worst with 317.9 total yards per game, their defense ranks third-best with only 234.9 total yards ceded per contest.
• Iowa ranks 52nd in the FBS with 31.3 points per contest, but it has been led by its defense, which ranks fourth-best by giving up only 13.1 points per contest.