Louisville vs. SMU Dunkel Predictions & Vegas Odds - Jan. 31

The No. 20 Louisville Cardinals (14-6, 4-4 ACC) host the SMU Mustangs (15-5, 4-3 ACC) at KFC Yum! Center, tipping off at 2 p.m. ET on Saturday, January 31, 2026. The Mustangs are 7.5-point underdogs in the game. The matchup's over/under is set at 164.5.

Their last time out, Louisville lost 83-52 to Duke on Monday. Ryan Conwell recorded 18 points, three rebounds and three assists for Louisville. SMU took care of business in its most recent outing 83-80 against Florida State on Saturday. Jaron Pierre Jr. scored a team-high 28 points for SMU in the victory.

Louisville vs. SMU Odds and Game Time

• When: Saturday, January 31, 2026 at 2 p.m. ET
• Where: KFC Yum! Center in Louisville, Kentucky
• Spread favorite: Louisville -7.5
• Over/Under: 164.5 points

How to watch Louisville vs. SMU

• TV Channel: ESPN
• Check out the rest of our Dunkel Index NCAA Basketball Picks!

Betting the Over/Under: Louisville vs. SMU

• Louisville and its opponents have hit the over on this game's total (164.5 points) six times this season.
• There have been 12 SMU games that finished with a combined score higher than 164.5 points this season.
• Together, the two teams combine for 173.3 points per game, 8.8 points more than the over/under of 164.5 for this matchup.
• These two teams surrender a combined 147.3 points per game, 17.2 points less than this contest's over/under.
• On average, the over/under in Louisville's games is 8.2 fewer points than the over/under of 164.5 in this matchup.
• A difference of 0.2 points separates this contest's over/under (164.5 points) and the average over/under in SMU's games (164.3) this season.

Betting the Spread: Louisville vs. SMU

• Louisville has played 20 games, with 11 wins against the spread.
• The Cardinals are 8-4 ATS when favored by 7.5 points or more this season.
• SMU is 9-10-1 against the spread this year.
• The Mustangs have covered the spread once this year when underdogs by 7.5 points or more (in two chances).
• Louisville is 10-2 overall, and 7-5 against the spread, at home.
• This season, as a 7.5-point favorite or more at home, Louisville is 6-3 ATS.
• SMU is 2-3 overall, and 3-1-1 against the spread, on the road.