Lakers vs. Spurs Dunkel NBA Picks, Predictions and Odds - Nov. 5

The Los Angeles Lakers (6-2) will try to continue a four-game winning streak when hosting the San Antonio Spurs (5-1) on November 5, 2025 at Crypto.com Arena.

Wednesday's matchup between the Lakers and the Spurs features the Lakers as 2.5-point favorites. The game has a point total of 227.5.

Lakers vs. Spurs Odds and Game Time

• Game day: Wednesday, November 5, 2025
• Game time: 10 p.m. ET
• Location: Los Angeles, California
• Arena: Crypto.com Arena
• Total: 227.5 points
• Spread: Lakers -2.5
• Moneyline: Lakers (-134), Spurs (+114)

How to watch Lakers vs. Spurs

• TV Channel: ESPN
• Live Stream: Fubo

Betting the Over/Under: Lakers vs. Spurs

• The Lakers' eight games this season have all gone over this contest's total of 227.5 points.
• The Spurs and their opponents have scored more than 227.5 combined points twice this season.
• The teams combine to score 238 points per game, 10.5 more points than this matchup's total.
• Opponents of these two teams combine to score 224.8 points per game, 2.7 fewer points than this matchup's total.

Betting the Spread: Lakers vs. Spurs

• Los Angeles has compiled a 6-2-0 record against the spread this season.
• The Lakers have been favored by 2.5 points or more two times this season, and covered the spread in both.
• The Spurs have a record of 2-2-2 against the spread this season.
• San Antonio has won its only game this year when playing as at least 2.5-point underdogs.
• The Lakers have two wins against the spread, and is 2-2 overall, at home this year.
• Los Angeles is unbeaten ATS (1-0) as a 2.5-point favorite or greater at home.
• The Spurs are 2-1 overall, with just one win against the spread, in away games.
• On the road, San Antonio is winless ATS (0-2) as 2.5-point underdogs or more.

Betting the Moneyline: Lakers vs. Spurs

• The Lakers have been listed as the moneyline favorite just two other times so far this season, and they won both of the games.
• The Spurs won the only game they've played as the underdog this season.
• Los Angeles has played as a moneyline favorite of -134 or shorter twice this season, and won both.
• San Antonio has played as an underdog of +114 or more once this season and won that game.
• The Lakers have a 57.3% chance to win this matchup based on the moneyline's implied probability.

Dunkel Index Prediction for Lakers vs. Spurs

• Pick ATS: Spurs (+ 2.5)
• Pick OU: Over (227.5)
  
• Prediction: Spurs 117 - Lakers 116
• Check out the rest of our Dunkel Index NBA Picks!