Loyola Chicago vs. Mercyhurst Dunkel Predictions & Vegas Odds - Nov. 6

The Loyola Chicago Ramblers (1-0) host the Mercyhurst Lakers (0-1) at Joseph J. Gentile Arena, beginning at 9 p.m. ET on Thursday, November 6, 2025. The Lakers are 20.5-point underdogs in the game. The matchup has a point total of 145.5.

In its last matchup on Monday, Loyola Chicago earned a 91-88 win against Cleveland State. Kayde Dotson scored a team-best 16 points for Loyola Chicago in the win. Mercyhurst's most recent contest was a 70-47 loss to Northwestern on Monday. Mercyhurst got a team-best 14 points from Jake Lemelman in the loss.

Loyola Chicago vs. Mercyhurst Odds and Game Time

• When: Thursday, November 6, 2025 at 9 p.m. ET
• Where: Joseph J. Gentile Arena in Chicago, Illinois
• Spread favorite: Loyola Chicago -20.5
• Over/Under: 145.5 points

How to watch Loyola Chicago vs. Mercyhurst

• TV Channel: Marquee Sports Network
• Live Stream: Fubo
• Check out the rest of our Dunkel Index NCAA Basketball Picks!

Betting the Over/Under: Loyola Chicago vs. Mercyhurst

• Loyola Chicago and its opponent combined to score over 145.5 points, the current matchup's total, in 15 of 32 games last season.
• Last year, eight of Mercyhurst's 28 games had a combined total higher than 145.5 points scored.
• These teams averaged a combined 141.4 points per game a season ago, 4.1 fewer points than the total of 145.5 set for this game.
• Opponents of the two teams averaged a combined 6.6 fewer points per game (138.9) last season than this matchup's total of 145.5 points.
• The average over/under Loyola Chicago had set in games last year was 3.0 fewer points than this outing's point total.
• The average over/under for Mercyhurst's games in 2024 was 7.7 fewer points than the point total of 145.5 for this game.

Betting the Spread: Loyola Chicago vs. Mercyhurst

• Loyola Chicago went 17-15-0 ATS last season.
• The Ramblers did not cover the spread when favored by 20.5 points or more last season (in three opportunities).
• Mercyhurst put together a 17-11-0 ATS record last season.
• The Lakers were an underdog by 20.5 points or more three times last year, and covered the spread in two of those games.
• Loyola Chicago was 15-1 overall, and 8-8 against the spread, at home last year.
• At home last year, Loyola Chicago was winless ATS (0-3) as a 20.5-point favorite or greater.
• Away from home last season, Mercyhurst was 4-14 overall and 9-9 against the spread.