Royals vs. Orioles Dunkel MLB Picks, Predictions and Prop Bets - April 22

The Kansas City Royals host the Baltimore Orioles at 2:10 p.m. ET on Wednesday, with both teams hoping to win the series. Michael Wacha (2-0, 1.00 ERA) will start for the Royals, who are 8-16 this season and fifth in the AL Central. Chris Bassitt (0-2, 6.19 ERA) is the expected starter for the Orioles, who are 11-13 and third in the AL East.

The Royals are moderate favorites on the moneyline (-131) at home over the Orioles (+111). The over/under in this contest is 9.5.

Royals vs. Orioles Odds, Game Time

• Game day: Wednesday, April 22, 2026
• Game time: 2:10 p.m. ET
• Location: Kansas City, Missouri
• Stadium: Kauffman Stadium
• Favorite: Royals (-131)
• Underdog: Orioles (+111)
• Over/under: 9.5

How to Watch Royals vs. Orioles

• TV Channel: ROYL and MASN
• Live Stream: Fubo (Watch for free)

Bet now on FanDuel Sportsbook!

Royals vs. Orioles: Betting the Moneyline

• The Royals have been the moneyline favorite 11 total times this season. They've gone 5-6 in those games.
• Baltimore has been pegged as an underdog in nine games this year and has walked away with the win two times (22.2%) in those games.
• Kansas City has a record of 3-4 in games when bookmakers favor them by at least -131 on the moneyline.
• The Orioles have a win-loss record of 1-2 when favored by +111 or worse by sportsbooks this year.
• Based on this contest's moneyline, the Royals have an implied win probability of 56.7%.
• The moneyline set for this matchup implies the Orioles have a 47.4% chance of walking away with the win.

Royals vs. Orioles: Betting the Spread & Total

• The Royals have combined with opponents to hit the over on the total nine times this season for a 9-15-0 record against the over/under.
• Baltimore and its opponents have gone over the total this season in 14 of its 24 opportunities.
• The Royals are 8-16-0 ATS this season.
• The Orioles have an against the spread record of 10-14-0 in 24 games with a line this season.