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Astros vs. Rockies Dunkel MLB Picks, Predictions and Prop Bets - April 16

16 April 2026 By Data Skrive

The Colorado Rockies will try to snap a six-game losing streak when visiting the Houston Astros at 8:10 p.m. ET on Thursday. Ryan Weiss (0-2, 7.36 ERA) gets the start for the Astros, who are 8-11 this season and fourth in the AL West. Juan Mejia (0-2, 5.40 ERA) is the expected starter for the Rockies, who are 6-12 and fourth in the NL West.

With the Rockies (+143) visiting, the Astros (-171) are a solid favorite on the moneyline. The contest has a total set at 8.5.

Astros vs. Rockies Odds, Game Time

  • Game day: Thursday, April 16, 2026
  • Game time: 8:10 p.m. ET
  • Location: Houston, Texas
  • Stadium: Daikin Park
  • Favorite: Astros (-171)
  • Underdog: Rockies (+143)
  • Over/under: 8.5

How to Watch Astros vs. Rockies

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Astros vs. Rockies: Betting the Moneyline

  • The Astros have won 41.7% of the games this season when they were favored on the moneyline (5-7).
  • Colorado has come away with six wins in the 18 contests it has been listed as the underdogs in this season.
  • Houston is 2-2 this season when entering a game favored by -171 or more on the moneyline.
  • This year, the Rockies have won two of 13 games when listed as at least +143 or worse on the moneyline.
  • The implied moneyline probablility for this matchup gives the Astros a 63.1% chance to win.
  • Sportsbooks have implied with the moneyline set for this matchup that the Rockies have a 41.2% chance of pulling out a win.

Astros vs. Rockies: Betting the Spread & Total

  • The Astros have had an over/under set by oddsmakers 19 times, and have combined with opponents to go over the total in 13 of those games (13-6-0).
  • So far this season, Colorado and its opponents have hit the over in seven of its 18 games with a total.
  • The Astros have covered 42.1% of their games this season, going 8-11-0 against the spread.
  • In 18 games with a line this season, the Rockies have a mark of 11-7-0 against the spread.
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