Astros vs. Athletics Dunkel MLB Picks, Predictions and Prop Bets - Sept. 26

Yordan Alvarez rides a 10-game hitting streak into the Houston Astros' game versus the Athletics at 9:40 p.m. ET on Saturday, at Sutter Health Park. Hayden Wesneski (5-2, 3.50 ERA) will start for the Astros, who are 79-81 this season and first in the AL West. Jack Perkins (3-12, 5.90 ERA) is the expected starter for the Athletics, who are 64-96 and fourth in the AL West.

Despite playing away from home the Astros are at -161 to win, compared to the Athletics at +132. The game's over/under is 9.5.

Astros vs. Athletics Odds, Game Time

• Game day: Saturday, September 26, 2026
• Game time: 9:40 p.m. ET
• Location: West Sacramento, California
• Stadium: Sutter Health Park
• Favorite: Astros (-161)
• Underdog: Athletics (+132)
• Over/under: 9.5

How to Watch Astros vs. Athletics

• TV Channel: NBCS-CA and SCHN
• Live Stream: Fubo (Watch for free)

Bet now on FanDuel Sportsbook!

Astros vs. Athletics: Betting the Moneyline

• The Astros are 34-35 in games they were listed as the moneyline favorite (winning 49.3% of those games).
• The Athletics have won in 48, or 38.7%, of the 124 contests they have been named as odds-on underdogs in this year.
• This season, the Astros have won eight of their 20 games, or 40%, when favored by at least -161 on the moneyline.
• This year, the Athletics have won 20 of 57 games when listed as at least +132 or better on the moneyline.
• The implied moneyline probablility for this matchup gives the Astros a 61.7% chance to win.
• The Athletics have an implied victory probability of 43.1% according to the moneyline set for this matchup.

Astros vs. Athletics: Betting the Spread & Total

• The Astros have combined with their opponents to hit the over on the total 78 times this season for a 78-72-10 record against the over/under.
• The Athletics and their opponents have hit the over in 83 of their 160 games with a total this season.
• The Astros have gone 83-77-0 against the spread this season.
• The Athletics have an against the spread mark of 77-83-0 in 160 games with a line this season.