Rams vs. Cardinals Week 10 Dunkel NFL Picks, Predictions and Odds

Having won three in a row, the Los Angeles Rams (5-4) will face the Arizona Cardinals (3-6). The Rams are solid favorites, expected to win by at least a touchdown (currently -9.5). An over/under of 40.5 points has been established for the matchup.

The Rams are totaling 23.8 points per game on offense (13th in NFL), and they rank eighth on the other side of the ball with 20.1 points allowed per game. In terms of total offense, the Cardinals rank 22nd in the NFL (318.0 total yards per game) and 18th defensively (337.4 total yards allowed per contest).

Rams vs. Cardinals Odds and Game Time

• Date: Sunday, November 15, 2026
• Time: 4:05 p.m. ET
• City: Glendale, Arizona
• Venue: State Farm Stadium
• Total: 40.5 points
• Spread: Rams -9.5
• Moneyline: Rams (-455), Cardinals (+350)

How to watch Rams vs. Cardinals

• TV Channel: CBS

Betting the Over/Under: Rams vs. Cardinals

• The Rams and their opponents have combined to score more than 40.5 points in four of nine games this season.
• So far this season, four of Los Angeles' nine games have hit the over.
• The Cardinals have played five games this season that finished with a combined score over 40.5 points.
• In 2026, five Arizona games have gone over the point total.
• These two teams score 43.6 points per game combined, 3.1 more than this game's point total.
• Opponents of these teams average 48.4 combined points per game, 7.9 more points than this matchup's over/under.

Betting the Spread: Rams vs. Cardinals

• Los Angeles has put together a 4-5-0 record against the spread this season.
• Los Angeles has not covered the spread when favored by 9.5 points or more this season (in one opportunity).
• The Cardinals have won four games against the spread this season, failing to cover five times.
• Arizona has covered the spread when playing as at least 9.5-point underdogs in two of two chances this season.
• The Cardinals are winless against the spread, and 0-3 overall, at home this year.
• The Rams are 3-1 overall with two wins against the spread on the road.

Betting the Moneyline: Rams vs. Cardinals

• Los Angeles has been favored on the moneyline nine total times this season. They've gone 5-4 in those games.
• This season, the Cardinals have been the underdog eight times and won three of those games.
• Los Angeles has played as a moneyline favorite of -455 or shorter in only one game this season, which it lost.
• Arizona is undefeated in two games this season when it is the underdog by +350 or more on the moneyline.
• Based on this matchup's moneyline, the Rams' implied win probability is 82.0%.

Dunkel Prediction for Rams vs. Cardinals

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