Tigers vs. Guardians Dunkel MLB Picks, Predictions and Prop Bets - Sept. 18
18 September 2025

The Cleveland Guardians have a 2-0 series lead and hope to sweep the Detroit Tigers on Thursday at Comerica Park, at 1:10 p.m. ET. Tarik Skubal (13-5, 2.26 ERA) gets the start for the Tigers, who are 85-67 this season and first in the AL Central. Tanner Bibee (10-11, 4.44 ERA) is the expected starter for the Guardians, who are 80-71 and second in the AL Central.
The sportsbooks have spoken, making the Tigers (-210) a moderate moneyline favorite to defeat the Guardians (+173) at home. The contest has a total set at 7.5.
Tigers vs. Guardians Odds, Game Time
- Game day: Thursday, September 18, 2025
- Game time: 1:10 p.m. ET
- Location: Detroit, Michigan
- Stadium: Comerica Park
- Favorite: Tigers (-210)
- Underdog: Guardians (+173)
- Over/under: 7.5
How to Watch Tigers vs. Guardians
- TV Channel: Cleveland Guardians (NEW)
- Live Stream: Fubo (Watch for free)
Tigers vs. Guardians: Betting the Moneyline
- The Tigers have gone 63-43 in games they were listed as the moneyline favorite (winning 59.4% of those games).
- Cleveland has won in 39, or 46.4%, of the 84 contests it has been named as odds-on underdogs in this year.
- Detroit has a record of 13-3, a 81.2% win rate, when favored by -210 or more by oddsmakers this season.
- The Guardians have yet to win this season when listed as an underdog of +173 or worse on the moneyline this season.
- The implied moneyline probablility for this matchup gives the Tigers a 67.7% chance to win.
- The Guardians have an implied victory probability of 36.6% according to the moneyline set by sportsbooks for this matchup.
Tigers vs. Guardians: Betting the Spread & Total
- In the 152 games in which bookmakers have set an over/under for the Tigers, they have combined with opponents to go over the total 80 times (80-65-7).
- Cleveland and its opponents have gone over the total this season in 63 of its 149 opportunities.
- The Tigers have a 72-80-0 record against the spread this season.
- The Guardians have posted a record of 78-71-0 against the spread this season.
