Creighton vs. South Dakota Dunkel Predictions & Vegas Odds - Nov. 5

The No. 23 Creighton Bluejays (0-0) host the South Dakota Coyotes (0-1) at CHI Health Center Omaha, starting at 8 p.m. ET on Wednesday, November 5, 2025. The Bluejays are 28.5-point favorites in the game. The matchup's over/under is set at 167.5.

Creighton went 25-11 a season ago. South Dakota's most recent game was an 81-79 overtime loss to Utah Tech on Monday. South Dakota got a team-leading 23 points from Isaac Bruns in the loss.

Creighton vs. South Dakota Odds and Game Time

• When: Wednesday, November 5, 2025 at 8 p.m. ET
• Where: CHI Health Center Omaha in Omaha, Nebraska
• Spread favorite: Creighton -28.5
• Moneyline favorite: Creighton -50000
• Moneyline underdog: South Dakota +4000
• Over/Under: 167.5 points

How to watch Creighton vs. South Dakota

• TV Channel: Peacock
• Check out the rest of our Dunkel Index NCAA Basketball Picks!

Betting the Over/Under: Creighton vs. South Dakota

• Creighton and its opponent combined to score over 167.5 points, the current matchup's total, once last year.
• Last year, 19 of South Dakota's 29 games had a combined total higher than 167.5 points scored.
• The two teams averaged a combined 6.8 fewer points per game (160.7) a season ago than this game's total of 167.5 points.
• Opponents of these two teams averaged a combined 153.7 points per game last season, 13.8 fewer than the over/under in this game.
• The average total Creighton had set in matchups last year was 22.0 fewer points than this outing's point total.
• The average over/under in South Dakota's games in 2024 was 1.4 more points than the point total of 167.5 for this outing.

Betting the Spread: Creighton vs. South Dakota

• Creighton went 21-14-1 ATS last season.
• The Bluejays were favored by 28.5 points or more last season three times and failed to cover in all three.
• South Dakota went 15-14-0 ATS last season.
• At home last year, Creighton was 15-2 overall and 10-6-1 against the spread.
• At home last season, Creighton was winless ATS (0-3) as a 28.5-point favorite or greater.
• South Dakota was 6-9 against the spread, and 4-11 overall, away from home last season.

Betting the Moneyline: Creighton vs. South Dakota

• Creighton was the moneyline favorite 24 total times last season. It finished 20-4 in those games.
• The Bluejays did not play a game last season with moneyline odds of -50000 or shorter.
• The implied moneyline probability for this matchup gives Creighton a 99.8% chance to win.
• Last season, South Dakota won four out of the 16 games, or 25%, in which it was the underdog.
• The Coyotes were not a bigger underdog last season than the +4000 moneyline set for this game.
• The implied probability of a win by South Dakota, based on the moneyline, is 2.4%.