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Orioles vs. Astros Dunkel MLB Picks, Predictions and Prop Bets - April 28

28 April 2026 By Data Skrive

The Houston Astros will look to Yordan Alvarez, currently on a 12-game hitting streak, versus the Baltimore Orioles at 6:35 p.m. ET on Tuesday, at Oriole Park at Camden Yards. Shane Baz (0-2, 5.08 ERA) gets the start for the Orioles, who are 13-15 this season and third in the AL East. Kai-Wei Teng (1-1, 2.16 ERA) is starting for the Astros, who are 11-18 and fifth in the AL West.

With the Astros (+116) visiting, the Orioles (-138) are a solid favorite on the moneyline. The contest has a total set at 9.

Orioles vs. Astros Odds, Game Time

  • Game day: Tuesday, April 28, 2026
  • Game time: 6:35 p.m. ET
  • Location: Baltimore, Maryland
  • Stadium: Oriole Park at Camden Yards
  • Favorite: Orioles (-138)
  • Underdog: Astros (+116)
  • Over/under: 9

How to Watch Orioles vs. Astros

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Orioles vs. Astros: Betting the Moneyline

  • The Orioles have been favored on the moneyline 18 total times this season. They've finished 10-8 in those games.
  • Houston has been pegged as an underdog in 13 games this year and has walked away with the win six times (46.2%) in those games.
  • Baltimore has entered eight games this season favored by -138 or more and is 5-3 in those contests.
  • This season, the Astros have come away with a win two times in eight chances when named as an underdog of at least +116 or longer on the moneyline.
  • The Orioles have a 58% chance to win this game based on the moneyline's implied probability.
  • The Astros have an implied victory probability of 46.3% according to the moneyline set by sportsbooks for this matchup.

Orioles vs. Astros: Betting the Spread & Total

  • In the 28 games in which bookmakers have set an over/under for the Orioles, they have combined with opponents to go over the total 18 times (18-10-0).
  • So far this season, Houston and its opponents have hit the over in 21 of its 29 games with a total.
  • The Orioles have a 12-16-0 record against the spread this season (covering 42.9% of the time).
  • The Astros are 11-18-0 against the spread in their 29 games with a line set by sportsbooks this season.
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