Padres vs. Cardinals Dunkel MLB Picks, Predictions and Prop Bets - May 10

The San Diego Padres host the St. Louis Cardinals at 4:10 p.m. ET on Sunday. Walker Buehler (2-2, 5.64 ERA) will start for the Padres, who are 23-16 this season and second in the NL West. Kyle Leahy (4-3, 4.93 ERA) is expected to start for the Cardinals, who are 23-16 and second in the NL Central.

At home, the Padres are favored to win on the moneyline (-133) over the Cardinals (+111). The game's over/under is 8.

Padres vs. Cardinals Odds, Game Time

• Game day: Sunday, May 10, 2026
• Game time: 4:10 p.m. ET
• Location: San Diego, California
• Stadium: Petco Park
• Favorite: Padres (-133)
• Underdog: Cardinals (+111)
• Over/under: 8

How to Watch Padres vs. Cardinals

• TV Channel: SDPA and CARD
• Live Stream: Fubo (Watch for free)

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Padres vs. Cardinals: Betting the Moneyline

• The Padres are 13-10 in games they were favored on the moneyline (winning 56.5% of those games).
• St. Louis has been underdogs in 35 games this season and has come away with the win 21 times (60%) in those contests.
• This season San Diego has won 10 of its 17 games, or 58.8%, when favored by at least -133 on the moneyline.
• The Cardinals have a win-loss record of 12-11 when favored by +111 or worse by bookmakers this year.
• The Padres have an implied moneyline win probability of 57.1% in this game.
• The moneyline set for this matchup implies the Cardinals have a 47.4% chance of walking away with the win.

Padres vs. Cardinals: Betting the Spread & Total

• The Padres have played in 39 games with a set over/under, and have combined with their opponents to go over the total 16 times (16-21-2).
• So far this season, St. Louis and its opponents have hit the over in 17 of its 39 games with a total.
• The Padres have covered 56.4% of their games this season, going 22-17-0 ATS.
• The Cardinals are 24-15-0 against the spread in their 39 games that had a posted line this season.