Padres vs. Giants Dunkel MLB Picks, Predictions and Prop Bets - Sept. 12

The San Diego Padres bring a five-game winning streak into a road contest versus the San Francisco Giants at 4:05 p.m. ET on Saturday. Michael King (10-9, 3.00 ERA) gets the start for the Padres, who are 79-68 this season and second in the NL West. Cesar Perdomo (0-0, 0.90 ERA) is starting for the Giants, who are 62-86 and fourth in the NL West.

Despite playing on the road, the Padres are still a decent moneyline favorite (-158) over the Giants (+129). The contest has an over/under set at 7.5.

Padres vs. Giants Odds, Game Time

• Game day: Saturday, September 12, 2026
• Game time: 4:05 p.m. ET
• Location: San Francisco, California
• Stadium: Oracle Park
• Favorite: Padres (-158)
• Underdog: Giants (+129)
• Over/under: 7.5

How to Watch Padres vs. Giants

• TV Channel: NBCS-BA and SDPA
• Live Stream: Fubo (Watch for free)

Bet now on FanDuel Sportsbook!

Padres vs. Giants: Betting the Moneyline

• The Padres have won 41 of the 70 games they were listed as the moneyline favorite this season (58.6%).
• San Francisco has been victorious in 37, or 37.8%, of the 98 contests it has been chosen as underdogs in this season.
• This season San Diego has won 12 of its 18 games, or 66.7%, when favored by at least -158 on the moneyline.
• This season, the Giants have come away with a win 14 times in 36 chances when named as an underdog of at least +129 or longer on the moneyline.
• Based on this matchup's moneyline, the Padres' implied win probability is 61.2%.
• The moneyline set for this matchup implies the Giants have a 43.7% chance of walking away with the win.

Padres vs. Giants: Betting the Spread & Total

• The Padres have played in 147 games with set over/under, and have combined with opponents to go over the total 65 times (65-77-5).
• San Francisco and its opponents have gone over the total this season in 70 of its 147 opportunities.
• The Padres have covered 56.5% of their games this season, going 83-64-0 against the spread.
• The Giants have posted a record of 73-74-0 against the spread this season.