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Pirates vs. Athletics Dunkel MLB Picks, Predictions and Prop Bets - Sept. 21

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21 September 2025 By Data Skrive

The Pittsburgh Pirates and Athletics square off on Sunday at 1:35 p.m. ET at PNC Park, attempting to break a 1-1 series tie. Mike Burrows (2-4, 4.10 ERA) will start for the Pirates, who are 66-89 this season and fifth in the NL Central. Mitch Spence (3-5, 4.48 ERA) is the expected starter for the Athletics, who are 73-82 and fourth in the AL West.

Oddsmakers have made the Pirates a decent moneyline favorite (-122) at home over the Athletics (+102). The over/under in this contest is set at 8.5.

Pirates vs. Athletics Odds, Game Time

Game day: Sunday, September 21, 2025
Game time: 1:35 p.m. ET
Location: Pittsburgh, Pennsylvania
Stadium: PNC Park
Favorite: Pirates (-122)
Underdog: Athletics (+102)
Over/under: 8.5

How to Watch Pirates vs. Athletics

TV Channel: SportsNet Pittsburgh
Live Stream: Fubo (Watch for free)

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Pirates vs. Athletics: Betting the Moneyline

The Pirates have been favored on the moneyline 44 total times this season. They've finished 21-23 in those games.
The Athletics have been victorious in 55, or 47.4%, of the 116 contests they have been chosen as underdogs in this season.
This season, the Pirates have won 15 of their 31 games, or 48.4%, when favored by at least -122 on the moneyline.
This year, the Athletics have won 43 of 101 games when listed as at least +102 or better on the moneyline.
The Pirates have a 55% chance to win this matchup based on the moneyline's implied probability.
The Athletics have an implied victory probability of 49.5% according to the moneyline set by sportsbooks for this matchup.

Pirates vs. Athletics: Betting the Spread & Total

The Pirates have combined with their opponents to hit the over on the total 62 times this season for a 62-87-5 record against the over/under.
Games involving the Athletics have gone over the total set by oddsmakers in 73 of 155 chances this season.
The Pirates have covered 53.2% of their games this season, going 82-72-0 ATS.
The Athletics are 82-73-0 against the spread in their 155 games with a line set by sportsbooks this season.

Dunkel Index Prediction for Pirates vs. Athletics

Pick OU: Under (8.5)
Prediction: Athletics 4 - Pirates 3

Check out all the Dunkel Index MLB Baseball Picks!

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About the author

Data Skrive

Data Skrive creates sports articles about every player, on every team, in every league, for every game, for every fan. Data Skrive know sports. With over 100M monthly readers across 500+ websites and 200+ DMAs, their innovative Fan Engagement Solution creates engaging and entertaining sports content that fans value to drive revenue for their customers. Sports never stop, and covering every topic at the right time is not feasible. Data Skrive's technology is able to cover highly relevant topics that are interesting and engaging to your fans.