Florida State vs. Stanford Dunkel NCAA Football Picks, Predictions and Odds - Oct. 18

Oddsmakers heavily favor the Florida State Seminoles (3-3) when they visit the Stanford Cardinal (2-4) on Saturday, October 18, 2025 in a matchup between ACC foes at Stanford Stadium. Florida State is favored by 17.5 points.

In their last game, the Seminoles lost against the Pittsburgh Panthers, 34-31.

In their most recent contest, the Cardinal lost against the SMU Mustangs, 34-10.

Florida State vs. Stanford Predictions

For predictions on the upcoming game between the Florida State Seminoles and Stanford Cardinal, computer-derived against-the-spread, over/under, and score predictions are below, sourced from Dunkel Index.

• Pick ATS: Cardinal (+ 17.5)
• Pick OU: Under (54.5)
• Prediction: Seminoles 29 - Cardinal 19

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Florida State vs. Stanford Moneylines

Grab a peek below at the most up-to-date moneylines for the Seminoles-Cardinal matchup.

• Florida State Moneyline: -980
• Stanford Moneyline: +643

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Florida State Betting Insights

• Florida State is 1-2 in games it was favored on the moneyline (winning 33.3% of those games).
• Florida State has played as a moneyline favorite of -980 or shorter in only one game this season, which it won.
• The Seminoles and their opponents have scored more than 54.5 points in three of six games this season.
• The average total in Seminoles outings this year is 55.2, 0.7 more than this matchup's over/under.
• The Seminoles are the fifth-highest scoring team in college football this year. The Cardinal have scored the 123rd-most points.

Stanford Betting Insights

• This season, Stanford has won one out of the five games in which it has been the underdog.
• Stanford has been at least a +643 moneyline underdog two times this season, but lost all of those games.
• Stanford and its opponents have combined to score more than 54.5 points twice this season.
• Stanford's contests this season have a 49.2-point average over/under, 5.3 fewer points than this game's total.

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Key Stats for Florida State vs. Stanford

• The Seminoles sport the 44th-ranked defense this season (333.0 yards allowed per game), and they've been more effective on the other side of the ball, ranking third-best with 536.5 yards per game.
• Florida State ranks 60th in scoring defense this season (23.0 points allowed per game), but has been thriving on the other side of the ball, ranking fifth-best in the FBS with 44.2 points per game.
• The Cardinal rank 108th in total yards per game (333.5), but they've been worse defensively, ranking 21st-worst in the FBS with 418.3 total yards surrendered per contest.
• This season has been hard for Stanford on both offense and defense, as it is compiling just 18.8 points per contest (17th-worst) and ceding 30.2 points per game (19th-worst).