Cubs vs. Pirates Dunkel MLB Picks, Predictions and Prop Bets - Sept. 12

Pete Crow-Armstrong has 160 RBIs, and will try to get his 100th when his Chicago Cubs play the Pittsburgh Pirates on Saturday at 2:20 p.m. ET. Clay Holmes (6-7, 2.83 ERA) gets the start for the Cubs, who are 82-66 this season and second in the NL Central. Paul Skenes (10-11, 3.83 ERA) is starting for the Pirates, who are 74-74 and third in the NL Central.

At home, the Cubs are favored to win on the moneyline (-125) over the Pirates (+102). The game has an over/under of 9 runs.

Cubs vs. Pirates Odds, Game Time

• Game day: Saturday, September 12, 2026
• Game time: 2:20 p.m. ET
• Location: Chicago, Illinois
• Stadium: Wrigley Field
• Favorite: Cubs (-125)
• Underdog: Pirates (+102)
• Over/under: 9

How to Watch Cubs vs. Pirates

• TV Channel: MARQ and SportsNet PT
• Live Stream: Fubo (Watch for free)

Bet now on FanDuel Sportsbook!

Cubs vs. Pirates: Betting the Moneyline

• The Cubs have won 56.4% of the games this season when they were favored on the moneyline (57-44).
• Pittsburgh has won in 30, or 42.9%, of the 70 contests it has been named as odds-on underdogs in this year.
• Chicago has a record of 46-37, a 55.4% win rate, when favored by -125 or more by oddsmakers this season.
• This season, the Pirates have been victorious 20 times in 48 chances when named as an underdog of at least +102 or worse on the moneyline.
• The Cubs have a 55.6% chance to win this matchup based on the moneyline's implied probability.
• The moneyline set for this matchup implies the Pirates have a 49.5% chance of coming away with a victory in the contest.

Cubs vs. Pirates: Betting the Spread & Total

• The Cubs have had an over/under set by bookmakers 148 times, and have combined with opponents to go over the total in 82 of those games (82-62-4).
• So far this season, Pittsburgh and its opponents have hit the over in 76 of its 148 games with a total.
• The Cubs have gone 70-78-0 ATS this season.
• The Pirates have posted a record of 70-78-0 against the spread this season.