Orioles vs. Blue Jays Dunkel MLB Picks, Predictions and Prop Bets - Sept. 22

The Baltimore Orioles meet the Toronto Blue Jays after Pete Alonso homered twice in a 4-3 victory over the Blue Jays. The game starts at 6:35 p.m. ET on Tuesday. Chris Bassitt (8-5, 4.64 ERA) gets the start for the Orioles, who are 76-81 this season and fifth in the AL East. Max Scherzer (3-8, 6.07 ERA) is the expected starter for the Blue Jays, who are 77-80 and fourth in the AL East.

Oddsmakers have made the Orioles a decent moneyline favorite (-122) at home over the Blue Jays (+101). The total for the Orioles-Blue Jays game is set at 7.5.

Orioles vs. Blue Jays Odds, Game Time

• Game day: Tuesday, September 22, 2026
• Game time: 6:35 p.m. ET
• Location: Baltimore, Maryland
• Stadium: Oriole Park at Camden Yards
• Favorite: Orioles (-122)
• Underdog: Blue Jays (+101)
• Over/under: 7.5

How to Watch Orioles vs. Blue Jays

• TV Channel: MASN and SNET
• Live Stream: Fubo (Watch for free)

Bet now on FanDuel Sportsbook!

Orioles vs. Blue Jays: Betting the Moneyline

• The Orioles have won 52.9% of the games this season when they were favored on the moneyline (36-32).
• Toronto has come away with 32 wins in the 71 contests it has been listed as the underdogs in this season.
• Baltimore is 28-25 this season when entering a game favored by -122 or more on the moneyline.
• This season, the Blue Jays have come away with a win 23 times in 51 chances when named as an underdog of at least +101 or longer on the moneyline.
• The Orioles have an implied moneyline win probability of 55% in this contest.
• The Blue Jays have an implied victory probability of 49.8% according to the moneyline set for this matchup.

Orioles vs. Blue Jays: Betting the Spread & Total

• The Orioles have played in 157 games with over/under set, and have combined with opponents to go over the total 79 times (79-75-3).
• So far this season, Toronto and its opponents have hit the over in 80 of its 157 games with a total.
• The Orioles are 82-75-0 against the spread this season.
• The Blue Jays are 78-79-0 against the spread in their 157 games that had a posted line this season.