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Angels vs. Athletics Dunkel MLB Picks, Predictions and Prop Bets - Sept. 22

22 September 2026 By Data Skrive

The Athletics take a six-game losing streak into a contest versus the Los Angeles Angels, at 9:40 p.m. ET on Tuesday. Yusei Kikuchi (1-6, 5.02 ERA) will start for the Angels, who are 60-96 this season and fifth in the AL West. Brady Basso (1-3, 4.50 ERA) is expected to start for the Athletics, who are 61-95 and fourth in the AL West.

With moneyline odds of -111 for the Angels versus -109 for the Athletics, this game should be a close one. The game has an over/under of 9.5 runs.

Angels vs. Athletics Odds, Game Time

  • Game day: Tuesday, September 22, 2026
  • Game time: 9:40 p.m. ET
  • Location: West Sacramento, California
  • Stadium: Sutter Health Park
  • Favorite: Angels (-111)
  • Underdog: Athletics (-109)
  • Over/under: 9.5

How to Watch Angels vs. Athletics

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Angels vs. Athletics: Betting the Moneyline

  • The Angels have won 50% of the games this season when they were the moneyline favorite (14-14).
  • The Athletics have won in 45, or 37.5%, of the 120 contests they have been named as odds-on underdogs in this year.
  • The Angels have a record of 14-12, a 53.8% win rate, when they're favored by -111 or more by sportsbooks this season.
  • This year, the Athletics have won 44 of 118 games when listed as at least -109 or better on the moneyline.
  • Based on this game's moneyline, the Angels have an implied win probability of 52.6%.
  • Oddsmakers have implied with the moneyline set for this matchup that the Athletics have a 52.2% chance of pulling out a win.

Angels vs. Athletics: Betting the Spread & Total

  • The Angels have combined with their opponents to go over the total 65 times this season for a 65-85-6 record against the over/under.
  • The Athletics and their opponents have hit the over in 79 of their 156 games with a total this season.
  • The Angels are 80-76-0 ATS this season.
  • The Athletics have posted a record of 74-82-0 against the spread this season.
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