Xavier vs. Santa Clara Dunkel Predictions & Vegas Odds - Nov. 10

The Xavier Musketeers (2-0) host the Santa Clara Broncos (2-0) at Cintas Center, beginning at 8:30 p.m. ET on Monday, November 10, 2025. The Broncos are 2.5-point underdogs in the game. The matchup has an over/under of 157.5 points.

Xavier is coming off of a 74-69 win against Le Moyne in its most recent outing on Thursday. Malik Moore's team-leading 17 points paced Xavier in the win. Santa Clara came out on top in its last matchup 79-67 against McNeese on Friday. Aleksandar Gavalyugov's team-high 19 points paced Santa Clara in the victory.

Xavier vs. Santa Clara Odds and Game Time

• When: Monday, November 10, 2025 at 8:30 p.m. ET
• Where: Cintas Center in Cincinnati, Ohio
• Spread favorite: Xavier -2.5
• Moneyline favorite: Xavier -149
• Moneyline underdog: Santa Clara +124
• Over/Under: 157.5 points

How to watch Xavier vs. Santa Clara

• TV Channel: FOX Sports 1
• Live Stream: Fubo
• Check out the rest of our Dunkel Index NCAA Basketball Picks!

Betting the Over/Under: Xavier vs. Santa Clara

• Last season, Xavier's games went over 157.5 points scored, its current matchup's over/under, 10 (out of 34) times.
• A total of 15 Santa Clara's games last season (out of 32) had more than 157.5 total points scored.
• The Musketeers and the Broncos combined to average 2.5 more points per game a season ago than the total of 157.5 set for this matchup.
• The Musketeers and the Broncos saw their opponents average a combined 12.9 fewer points per game last season than the over/under of 157.5 set for this outing.
• The average total Xavier had set in matchups last year was 7.8 fewer points than this outing's point total.
• Santa Clara's games in 2024 averaged a total of 154.9 points, 2.6 fewer than the point total in this matchup.

Betting the Spread: Xavier vs. Santa Clara

• Xavier went 19-15-0 ATS last season.
• The Musketeers were 12-7 ATS last season when playing as at least 2.5-point favorites.
• Santa Clara put together a 17-15-0 ATS record last season.
• The Broncos were 5-3 ATS last season when playing as at least 2.5-point underdogs.
• Xavier was 15-2 overall, and 10-7 against the spread, at home last year.
• At home last year, as a 2.5-point favorite or greater, Xavier was 7-6 ATS.
• Santa Clara was 7-4 against the spread, and 6-5 overall, on the road last season.
• Santa Clara had two wins ATS (2-2) on the road as a 2.5-point underdog or more.

Betting the Moneyline: Xavier vs. Santa Clara

• Xavier won all 21 of the games in which it was favored on the moneyline last season.
• The Musketeers won all 18 games they played as a moneyline favorite with odds of -149 or shorter.
• Xavier has an implied moneyline win probability of 59.8% in this game.
• Santa Clara was an underdog 10 times last season and won three of those games.
• Last season, the Broncos won three of their eight games when they were an underdog by at least +124 on the moneyline.
• Bookmakers have implied with the moneyline set for this matchup that Santa Clara has a 44.6% chance to win.