NFL Predictions & Betting Odds - Week 12
18 November 2025
The Week 12 NFL schedule has plenty of quality competition in store. Among those contests is the Tampa Bay Buccaneers taking on the Los Angeles Rams.
We've got your back with a quick rundown on every NFL game this week with over/unders, spreads, moneylines, and Dunkel Index predictions. Continue reading for the details.
Bet now on FanDuel Sportsbook!Week 12 Games, Betting Info, and Predictions
There are 14 games on the NFL slate this week. Here's a look at each matchup:
Buffalo Bills (7-3) at Houston Texans (5-5)
- Game Time: 8:15 p.m. ET | Thursday, November 20, 2025
- Venue: NRG Stadium (Houston, Texas)
- Total: 43.5
- Spread: Bills (-5.5)
- Moneyline: Bills (-298), Texans (+240)
Dunkel Index predictions:
- Over/Under: Over (43.5)
- ATS: Texans (+5.5)
- Score Prediction: Texans 26, Bills 19
Pittsburgh Steelers (6-4) at Chicago Bears (7-3)
- Game Time: 1 p.m. ET | Sunday, November 23, 2025
- Venue: Soldier Field (Chicago, Illinois)
- Total: 45.5
- Spread: Bears (-3)
- Moneyline: Bears (-155), Steelers (+130)
Dunkel Index predictions:
- Over/Under: Over (45.5)
- ATS: Steelers (+3)
- Score Prediction: Bears 26, Steelers 24
New England Patriots (9-2) at Cincinnati Bengals (3-7)
- Game Time: 1 p.m. ET | Sunday, November 23, 2025
- Venue: Paycor Stadium (Cincinnati, Ohio)
- Total: 50.5
- Spread: Patriots (-7.5)
- Moneyline: Patriots (-441), Bengals (+340)
Dunkel Index predictions:
- Over/Under: Over (50.5)
- ATS: Patriots (-7.5)
- Score Prediction: Patriots 32, Bengals 19
New York Giants (2-9) at Detroit Lions (6-4)
- Game Time: 1 p.m. ET | Sunday, November 23, 2025
- Venue: Ford Field (Detroit, Michigan)
- Total: 50.5
- Spread: Lions (-10.5)
- Moneyline: Lions (-521), Giants (+390)
Dunkel Index predictions:
- Over/Under: Under (50.5)
- ATS: Lions (-10.5)
- Score Prediction: Lions 32, Giants 18
Minnesota Vikings (4-6) at Green Bay Packers (6-3-1)
- Game Time: 1 p.m. ET | Sunday, November 23, 2025
- Venue: Lambeau Field (Green Bay, Wisconsin)
- Total: 41.5
- Spread: Packers (-6.5)
- Moneyline: Packers (-325), Vikings (+260)
Dunkel Index predictions:
- Over/Under: Over (41.5)
- ATS: Packers (-6.5)
- Score Prediction: Packers 26, Vikings 18
New York Jets (2-8) at Baltimore Ravens (5-5)
- Game Time: 1 p.m. ET | Sunday, November 23, 2025
- Venue: M&T Bank Stadium (Baltimore, Maryland)
- Total: 44.5
- Spread: Ravens (-13.5)
- Moneyline: Ravens (-952), Jets (+625)
Dunkel Index predictions:
- Over/Under: Over (44.5)
- ATS: Ravens (-13.5)
- Score Prediction: Ravens 31, Jets 18
Seattle Seahawks (7-3) at Tennessee Titans (1-9)
- Game Time: 1 p.m. ET | Sunday, November 23, 2025
- Venue: Nissan Stadium (Nashville, Tennessee)
- Total: 40.5
- Spread: Seahawks (-12.5)
- Moneyline: Seahawks (-847), Titans (+575)
Dunkel Index predictions:
- Over/Under: Over (40.5)
- ATS: Seahawks (-12.5)
- Score Prediction: Seahawks 31, Titans 14
Indianapolis Colts (8-2) at Kansas City Chiefs (5-5)
- Game Time: 1 p.m. ET | Sunday, November 23, 2025
- Venue: GEHA Field at Arrowhead Stadium (Kansas City, Missouri)
- Total: 50.5
- Spread: Chiefs (-3.5)
- Moneyline: Chiefs (-185), Colts (+154)
Dunkel Index predictions:
- Over/Under: Under (50.5)
- ATS: Colts (+3.5)
- Score Prediction: Chiefs 25, Colts 24
Jacksonville Jaguars (6-4) at Arizona Cardinals (3-7)
- Game Time: 4:05 p.m. ET | Sunday, November 23, 2025
- Venue: State Farm Stadium (Glendale, Arizona)
- Total: 47.5
- Spread: Jaguars (-2.5)
- Moneyline: Jaguars (-148), Cardinals (+124)
Dunkel Index predictions:
- Over/Under: Under (47.5)
- ATS: Jaguars (-2.5)
- Score Prediction: Jaguars 27, Cardinals 21
Cleveland Browns (2-8) at Las Vegas Raiders (2-8)
- Game Time: 4:05 p.m. ET | Sunday, November 23, 2025
- Venue: Allegiant Stadium (Paradise, Nevada)
- Total: 36.5
- Spread: Raiders (-3.5)
- Moneyline: Raiders (-175), Browns (+145)
Dunkel Index predictions:
- Over/Under: Over (36.5)
- ATS: Browns (+3.5)
- Score Prediction: Raiders 21, Browns 19
Atlanta Falcons (3-7) at New Orleans Saints (2-8)
- Game Time: 4:25 p.m. ET | Sunday, November 23, 2025
- Venue: Caesars Superdome (New Orleans, Louisiana)
- Total: 39.5
- Spread: Saints (-1.5)
- Moneyline: Saints (-125), Falcons (+105)
Dunkel Index predictions:
- Over/Under: Over (39.5)
- ATS: Falcons (+1.5)
- Score Prediction: Saints 22, Falcons 21
Philadelphia Eagles (8-2) at Dallas Cowboys (4-5-1)
- Game Time: 4:25 p.m. ET | Sunday, November 23, 2025
- Venue: AT&T Stadium (Arlington, Texas)
- Total: 48.5
- Spread: Eagles (-3.5)
- Moneyline: Eagles (-185), Cowboys (+154)
Dunkel Index predictions:
- Over/Under: Over (48.5)
- ATS: Eagles (-3.5)
- Score Prediction: Eagles 30, Cowboys 21
Tampa Bay Buccaneers (6-4) at Los Angeles Rams (8-2)
- Game Time: 8:20 p.m. ET | Sunday, November 23, 2025
- Venue: SoFi Stadium (Inglewood, California)
- Total: 49.5
- Spread: Rams (-6.5)
- Moneyline: Rams (-325), Buccaneers (+260)
Dunkel Index predictions:
- Over/Under: Under (49.5)
- ATS: Rams (-6.5)
- Score Prediction: Rams 31, Buccaneers 17
Carolina Panthers (6-5) at San Francisco 49ers (7-4)
- Game Time: 8:15 p.m. ET | Monday, November 24, 2025
- Venue: Levi's Stadium (Santa Clara, California)
- Total: 48.5
- Spread: 49ers (-7)
- Moneyline: 49ers (-345), Panthers (+275)
Dunkel Index predictions:
- Over/Under: Under (48.5)
- ATS: 49ers (-7)
- Score Prediction: 49ers 29, Panthers 15
