Lions vs. Giants Week 12 Dunkel NFL Picks, Predictions and Odds

The New York Giants (2-9) will be aiming to end a five-game losing run against the Detroit Lions (6-4). The Lions are big favorites (-10.5). The expected point total for the matchup is set at 50.5.

The Lions have the 10th-ranked defense this year (21.6 points allowed per game), and they've been better offensively, ranking fourth-best with 29.2 points per game. The Giants rank 23rd in points per game (21.5), but they've been less productive on the other side of the ball, ranking fourth-worst in the NFL with 27.3 points ceded per contest.

Lions vs. Giants Odds and Game Time

• Date: Sunday, November 23, 2025
• Time: 1 p.m. ET
• City: Detroit, Michigan
• Venue: Ford Field
• Total: 50.5 points
• Spread: Lions -10.5
• Moneyline: Lions (-521), Giants (+390)

How to watch Lions vs. Giants

• TV Channel: FOX (WUPW-Toledo, OH)
• Live Stream: Fubo

Betting the Over/Under: Lions vs. Giants

• In five of 10 games this season, the Lions and their opponents have combined to total more than 50.5 points.
• Detroit games have gone over the point total five out of 10 times this season.
• The Giants have combined with their opponent to score more than 50.5 points in five of 11 games this season.
• In 2025, six New York games have hit the over.
• These teams average a combined 50.7 points per game, 0.2 more points than this matchup's over/under.
• Opponents of these two teams average 48.9 points per game combined, 1.6 fewer than this matchup's total.

Betting the Spread: Lions vs. Giants

• Detroit has covered the spread six times in 10 games this season.
• The Giants are 6-5-0 ATS this season.
• At home this year, the Lions are 3-1 against the spread and 3-1 overall.
• This season in away games, the Giants are 3-3 against the spread and 0-6 overall.

Betting the Moneyline: Lions vs. Giants

• Detroit has gone 5-1 in games they were favored on the moneyline (winning 83.3% of those games).
• The Giants have entered the game as underdogs 11 times this season and won twice.
• Detroit has a 2-1 record (winning 66.7% of its games) when playing as a moneyline favorite of -521 or shorter.
• New York has not entered a game this season with longer moneyline odds than +390.
• The implied moneyline probability in this matchup gives the Lions an 83.9% chance to win.

Dunkel Prediction for Lions vs. Giants

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