Villanova vs. Holy Cross Dunkel Predictions & Vegas Odds - Nov. 6

The Villanova Wildcats (0-1) host the Holy Cross Crusaders (0-1) at The William B. Finneran Pavilion, beginning at 7 p.m. ET on Friday, November 6, 2026. The Crusaders are 31.5-point underdogs in the game. The matchup's point total is set at 151.5.

Villanova dropped its last game 74-72 against Notre Dame on Sunday. Tyler Perkins' team-high 18 points paced Villanova in the loss. Holy Cross heads into this matchup after a 103-59 loss to Rhode Island on Tuesday. Kole Hanson scored a team-best 11 points for Holy Cross in the loss.

Villanova vs. Holy Cross Odds and Game Time

• When: Friday, November 6, 2026 at 7 p.m. ET
• Where: The William B. Finneran Pavilion in Bryn Mawr, Pennsylvania
• Spread favorite: Villanova -31.5
• Over/Under: 151.5 points

How to watch Villanova vs. Holy Cross

• TV Channel: ESPN+
• Check out the rest of our Dunkel Index NCAA Basketball Picks!

Betting the Over/Under: Villanova vs. Holy Cross

• Villanova and its opponent combined to score over 151.5 points, the current matchup's point total, in 14 of 33 games last season.
• Last year, 10 of Holy Cross' 31 games had a combined total of more than 151.5 points scored.
• The two teams averaged a combined 6.2 fewer points per game (145.3) a season ago than this game's total of 151.5 points.
• Opponents of these two teams averaged a combined 144.5 points per game last season, 7.0 fewer than the point total in this matchup.
• The average total Villanova had set in matchups last year was 3.1 fewer points than this outing's point total.
• The average over/under for Holy Cross' games in 2025 was 10.0 fewer points than the point total of 151.5 in this game.

Betting the Spread: Villanova vs. Holy Cross

• Villanova won 19 games against the spread last season, while failing to cover 14 times.
• Holy Cross put together a 16-15-0 record against the spread last season.
• The Crusaders were an underdog by 31.5 points or more last season once, and failed to cover the spread.
• At home last season, Villanova was 8-8 against the spread and 13-3 overall.
• Last year on the road, Holy Cross was 9-9 against the spread and 3-13 overall.