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Sabres vs. Blue Jackets NHL Predictions, Picks and Odds - Nov. 6

06 November 2026 By Data Skrive

The Buffalo Sabres and Columbus Blue Jackets -- the former coming off a loss, the latter a victory -- will play on Friday at 7 p.m. ET, at KeyBank Center in Buffalo. The bookmakers have made the Sabres solid favorites at -170 on the moneyline, and the Blue Jackets are at +142.

Buffalo fell 2-1 at home its last time out on Nov. 4 against the Ottawa Senators. Zachary Benson (one assist) and Tage Thompson (one assist) were among the three Sabres players who recorded one point each.

Columbus won 2-1 in a shootout in its most recent contest on Nov. 5 at home against the Dallas Stars, winning the shootout 2-0 to secure the victory. Three Blue Jackets players recorded one point each in that matchup, including Matthew Knies (one assist) and Zachary Kenneth Werenski (one goal).

Here is our pick for who will secure the victory in Friday's game.

Bet now on FanDuel Sportsbook!

Sabres vs. Blue Jackets Predictions & Pick

Ahead of the upcoming game between the Buffalo Sabres and Columbus Blue Jackets, computer-derived moneyline, over/under, and score predictions are below, sourced from Dunkel Index.

  • Prediction: Sabres 3 - Blue Jackets 2
  • Pick OU: Under 6.5 (Dunkel projecting 5 goals)

Pick with the best in the business! Get free picks for every game, every week at the Dunkel Index.

Sabres vs. Blue Jackets Moneylines

Snag a peek below at the most up-to-date moneylines for the Sabres-Blue Jackets matchup.

  • Favorite: Sabres (-170)
  • Underdog: Blue Jackets (+142)

Sabres Betting Insights

  • The Sabres have been victorious in five of their eight games when they were listed as a moneyline favorite this season (62.5%).
  • Buffalo has had moneyline odds of -170 or shorter in only two games this season, and split them 1-1.
  • Based on this game's moneyline, the Sabres have an implied probability of 63.0% to win.
  • In eight games this season, Buffalo and its opponent have combined for more than 6.5 goals.

Blue Jackets Betting Insights

  • The Blue Jackets have been listed as an underdog nine times this season, and won four of those games.
  • This season Columbus has been at least a +142 underdog on the moneyline three times, losing each of those contests.
  • Oddsmakers have implied, given the moneyline set for this matchup, that the Blue Jackets have a 41.3% chance to win.
  • Columbus has played six games this season that ended with more than 6.5 goals.

Sabres Key Stats

  • Buffalo ranks 24th in the NHL with 44 goals scored (2.9 per game).
  • Defensively, the Sabres are conceding 50 total goals (3.3 per game) to rank 15th in league play.
  • It has the league's 24th-ranked goal differential at -6.
  • The eight power-play goals the Sabres have recorded this season (on 49 power-play chances) rank 24th in the NHL.
  • Buffalo's 16.33% power-play conversion rate ranks 27th in the league.
  • The Sabres have capitalized with one shorthanded goal this season (16th among NHL teams).
  • Buffalo's 69.81% penalty-kill success rate ranks 27th in the league.
  • Buffalo has the 30th-ranked faceoff win percentage in the NHL, at 45.2%.
  • The Sabres make 10.5% of their shots (25th in the league).

Blue Jackets Key Stats

  • With 36 goals (2.6 per game), Columbus has the league's 32nd-ranked offense.
  • The Blue Jackets have one of the top defenses in the league, conceding 42 total goals (3.0 per game), fourth in the NHL.
  • With a goal differential of -6, the team is 24th in the league.
  • The Blue Jackets have six power-play goals (on 37 chances), 31st in the NHL.
  • Columbus has the NHL's 28th-ranked power-play percentage (16.22%).
  • Columbus' has the 24th-ranked penalty-kill percentage (73.17%).
  • At 53.2%, Columbus has the NHL's seventh-best faceoff win rate.
  • The Blue Jackets' 10.0% shooting percentage is 26th in the league.

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