UConn vs. DePaul Dunkel Predictions & Vegas Odds - Dec. 21

The No. 5 UConn Huskies (11-1, 1-0 Big East) take on the DePaul Blue Demons (8-4, 0-1 Big East) as 14.5-point favorites on Sunday, December 21, 2025 at 4:30 p.m. ET on Fox Sports 1. The matchup has an over/under of 137.5.

Last time out, UConn won on Tuesday 79-60 over Butler. Solomon Ball's team-leading 26 points led UConn in the victory. DePaul's most recent contest was a 79-66 loss to St. John's on Tuesday. Kaleb Banks' team-high 19 points paced DePaul in the loss.

UConn vs. DePaul Odds and Game Time

• When: Sunday, December 21, 2025 at 4:30 p.m. ET
• Where: Wintrust Arena in Chicago, Illinois
• Spread favorite: UConn -14.5
• Moneyline favorite: UConn -1587
• Moneyline underdog: DePaul +872
• Over/Under: 137.5 points

How to watch UConn vs. DePaul

• TV Channel: FOX Sports 2
• Live Stream: Fubo
• Check out the rest of our Dunkel Index NCAA Basketball Picks!

Betting the Over/Under: UConn vs. DePaul

• This season, UConn and its opponents have combined to outscore Sunday's total of 137.5 points seven times.
• Eight of DePaul's games have ended with a combined score over 137.5 points this season.
• The Huskies average 79 points per game against the Blue Demons' 76.4, totaling 17.9 points over the contest's total of 137.5.
• The 130.5 points per game these two teams surrender to opponents combined this season are 7.0 less than the 137.5-point over/under in this contest.
• On average, UConn has had a 140.7-point over/under in its games this season, 3.2 more points than the over/under in this contest.
• The over/under for this game is 7.7 points lower than the average over/under in DePaul's games this season of 145.2.

Betting the Spread: UConn vs. DePaul

• In UConn's 12 games this year, it has four wins against the spread.
• The Huskies have covered the spread twice this season when favored by 14.5 points or more (in six chances).
• DePaul has played 12 games, with seven wins against the spread.
• This season, the Blue Demons won ATS in their only game as an underdog of 14.5 points or more.
• At home this year, DePaul is 4-4 against the spread and 6-2 overall.
• This season, as a 14.5-point underdog or greater at home, DePaul is 3-4 ATS.

Betting the Moneyline: UConn vs. DePaul

• UConn has entered the game as moneyline favorites nine times this season and won eight of those games.
• The Huskies are undefeated in three games this season when favored by -1587 or more on the moneyline.
• UConn has a 94.1% chance to win this game based on the implied probability of the moneyline.
• DePaul has been a moneyline underdog in four games this season and has come away with the win one time (25%) in those contests.
• The Blue Demons have played as an underdog of +872 or more just one time this year and came away with a loss in that game.
• The moneyline set for this matchup implies DePaul has a 10.3% chance of walking away with the win.