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Cubs vs. Tigers Dunkel MLB Picks, Predictions and Prop Bets - July 22

22 July 2026 By Data Skrive

The Chicago Cubs host the Detroit Tigers at 8:10 p.m. ET on Wednesday, with both teams hoping to win the series. Colin Rea (7-6, 4.74 ERA) gets the start for the Cubs, who are 57-44 this season and second in the NL Central. Keider Montero (6-5, 3.22 ERA) is the expected starter for the Tigers, who are 47-54 and fourth in the AL Central.

With the Tigers (+103) visiting, the Cubs (-125) are a solid favorite on the moneyline. The total for this contest is set at 8.

Cubs vs. Tigers Odds, Game Time

  • Game day: Wednesday, July 22, 2026
  • Game time: 8:10 p.m. ET
  • Location: Chicago, Illinois
  • Stadium: Wrigley Field
  • Favorite: Cubs (-125)
  • Underdog: Tigers (+103)
  • Over/under: 8

How to Watch Cubs vs. Tigers

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Cubs vs. Tigers: Betting the Moneyline

  • The Cubs have won 56.3% of the games this season when they were the moneyline favorite (40-31).
  • Detroit has been underdogs in 44 games this season and has come away with the win 18 times (40.9%) in those contests.
  • Chicago has a record of 32-26 in games when bookmakers favor them by at least -125 on the moneyline.
  • This year, the Tigers have won 13 of 30 games when listed as at least +103 or worse on the moneyline.
  • Based on this game's moneyline, the Cubs' implied win probability is 55.6%.
  • The Tigers have an implied victory probability of 49.3% according to the moneyline set for this matchup.

Cubs vs. Tigers: Betting the Spread & Total

  • The Cubs have played in 101 games with an over/under set, and have combined with their opponents to go over the total 54 times (54-45-2).
  • Games involving Detroit have gone over the total set by sportsbooks in 44 of 101 chances this season.
  • The Cubs have gone 45-56-0 against the spread this season.
  • The Tigers are 53-48-0 against the spread in their 101 games that had a posted line this season.
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