Cardinals vs. Cubs Dunkel MLB Picks, Predictions and Prop Bets - July 29

The St. Louis Cardinals carry a three-game losing run into a home contest versus the Chicago Cubs, at 7:45 p.m. ET on Wednesday. Dustin May (5-7, 4.59 ERA) will start for the Cardinals, who are 53-54 this season and fourth in the NL Central. Matthew Boyd (6-1, 3.81 ERA) is expected to start for the Cubs, who are 61-46 and second in the NL Central.

The moneyline odds for the game between the Cardinals (-112) and Cubs (-109) suggest a close contest. The over/under for the Cardinals-Cubs game is 8.

Cardinals vs. Cubs Odds, Game Time

• Game day: Wednesday, July 29, 2026
• Game time: 7:45 p.m. ET
• Location: St. Louis, Missouri
• Stadium: Busch Stadium
• Favorite: Cardinals (-112)
• Underdog: Cubs (-109)
• Over/under: 8

How to Watch Cardinals vs. Cubs

• TV Channel: CARD and MARQ
• Live Stream: Fubo (Watch for free)

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Cardinals vs. Cubs: Betting the Moneyline

• The Cardinals have put together a 17-15 record in games they were listed as the moneyline favorite (winning 53.1% of those games).
• Chicago has been underdogs in 32 games this season and has come away with the win 18 times (56.2%) in those contests.
• St. Louis is 15-13 this season when entering a game favored by -112 or more on the moneyline.
• The Cubs have a win-loss record of 17-14 when favored by -109 or worse by bookmakers this year.
• Based on this game's moneyline, the Cardinals have an implied win probability of 52.8%.
• The moneyline set for this matchup implies the Cubs have a 52.2% chance of coming away with a victory in the contest.

Cardinals vs. Cubs: Betting the Spread & Total

• In the 107 games in which bookmakers have set an over/under for the Cardinals, they have combined with opponents to go over the total 41 times (41-58-8).
• Games involving Chicago have gone over the total set by oddsmakers in 58 of 107 chances this season.
• The Cardinals have collected a 59-48-0 record against the spread this season.
• The Cubs have an against the spread mark of 49-58-0 in 107 games with a line this season.