Cardinals vs. Diamondbacks Dunkel MLB Picks, Predictions and Prop Bets - June 22

The St. Louis Cardinals and Arizona Diamondbacks square off in the first of a four-game series on Monday at Busch Stadium, at 7:45 p.m. ET. Andre Pallante (8-4, 3.76 ERA) gets the start for the Cardinals, who are 41-34 this season and second in the NL Central. Merrill Kelly (5-6, 5.81 ERA) is expected to start for the Diamondbacks, who are 39-38 and third in the NL West.

Sportsbooks have made the Cardinals a decent moneyline favorite (-147) at home over the Diamondbacks (+120). The total for this contest is set at 8.5.

Cardinals vs. Diamondbacks Odds, Game Time

• Game day: Monday, June 22, 2026
• Game time: 7:45 p.m. ET
• Location: St. Louis, Missouri
• Stadium: Busch Stadium
• Favorite: Cardinals (-147)
• Underdog: Diamondbacks (+120)
• Over/under: 8.5

How to Watch Cardinals vs. Diamondbacks

• TV Channel: CARD and ARID
• Live Stream: Fubo (Watch for free)

Bet now on FanDuel Sportsbook!

Cardinals vs. Diamondbacks: Betting the Moneyline

• The Cardinals have won 68.4% of the games this season when they were favored on the moneyline (13-6).
• Arizona has come away with 16 wins in the 40 contests it has been listed as the underdogs in this season.
• St. Louis has played as favorites of -147 or more twice this season and won both games.
• This season, the Diamondbacks have come away with a win five times in 14 chances when named as an underdog of at least +120 or worse on the moneyline.
• Based on this contest's moneyline, the Cardinals' implied win probability is 59.5%.
• Sportsbooks have implied with the moneyline set for this matchup that the Diamondbacks have a 45.5% chance of pulling out a win.

Cardinals vs. Diamondbacks: Betting the Spread & Total

• The Cardinals have had an over/under set by bookmakers 75 times, and have combined with opponents to go over the total in 31 of those games (31-37-7).
• So far this season, Arizona and its opponents have hit the over in 34 of its 77 games with a total.
• The Cardinals have a 46-29-0 record against the spread this season (covering 61.3% of the time).
• In 77 games with a line this season, the Diamondbacks have a mark of 43-34-0 against the spread.