Seahawks vs. Colts Week 15 Dunkel NFL Picks, Predictions and Odds

Having won three in a row, the Seattle Seahawks (10-3) will face the Indianapolis Colts (8-5). The Seahawks are heavy favorites (-13.5). The matchup has an over/under of 42.5 points.

The Seahawks are totaling 353.5 yards per game on offense (ninth in NFL), and they rank sixth on the other side of the ball with 288.2 yards allowed per game. With 368.5 total yards per game on offense, the Colts rank sixth in the NFL in 2025. On defense, they rank 22nd, giving up 344.9 total yards per contest.

Seahawks vs. Colts Odds and Game Time

• Date: Sunday, December 14, 2025
• Time: 4:25 p.m. ET
• City: Seattle, Washington
• Venue: Lumen Field
• Total: 42.5 points
• Spread: Seahawks -13.5
• Moneyline: Seahawks (-1000), Colts (+650)

How to watch Seahawks vs. Colts

• TV Channel: CBS (KBAK-Bakersfield, CA)
• Live Stream: Fubo

Betting the Over/Under: Seahawks vs. Colts

• In nine of 13 games this season, the Seahawks and their opponents have combined to score more than 42.5 points.
• Seattle games have hit the over eight out of 13 times this season.
• The Colts have played 11 games this season that have had more than 42.5 combined points scored.
• In 2025, seven Indianapolis games have hit the over.
• The teams average 58.7 points per game combined, 16.2 more points than this game's total.
• These teams allow a combined 39.3 points per game, 3.2 fewer points than this contest's total.

Betting the Spread: Seahawks vs. Colts

• Seattle has compiled a 10-3-0 ATS record so far this year.
• The Colts are 7-6-0 ATS this season.
• The Seahawks are 4-2 overall, and 4-2 against the spread, at home.
• The Colts are 2-4 overall, and 3-3 against the spread, in away games.

Betting the Moneyline: Seahawks vs. Colts

• Seattle has won 90% of the games this season when it was the moneyline favorite (9-1).
• The Colts have won two of the four games they've played as underdogs this season.
• Seattle has yet to play a game with moneyline odds of -1000 or shorter.
• Indianapolis has not entered a game this season as a bigger underdog on the moneyline than the +650 odds on them winning this game.
• Based on this contest's moneyline, the Seahawks have an implied win probability of 90.9%.

Dunkel Prediction for Seahawks vs. Colts

For more expert NFL picks, visit our Dunkel Index NFL Picks and Predictions.