Rams vs. Giants Week 2 Dunkel NFL Picks, Predictions and Odds

The Los Angeles Rams (0-1) are considered favorites (-7) according to the oddsmakers ahead of their game versus the New York Giants (1-0) on September 21, 2026, starting at 8:15 p.m. ET, airing on ABC/ESPN. The expected point total for the matchup is set at 48.5.

The Rams ranked 10th in scoring defense last year (20.4 points allowed per game), but they excelled on offense, ranking best in the NFL with 30.5 points per game. The Giants put up 22.4 points per game offensively last season (17th in NFL), and they gave up 25.8 points per game (26th) on the other side of the ball.

Rams vs. Giants Odds and Game Time

• Date: Monday, September 21, 2026
• Time: 8:15 p.m. ET
• City: Inglewood, California
• Venue: SoFi Stadium
• Total: 48.5 points
• Spread: Rams -7
• Moneyline: Rams (-355), Giants (+280)

How to watch Rams vs. Giants

• TV Channel: ABC/ESPN

Betting the Over/Under: Rams vs. Giants

• Rams games last season featured more combined points than this contest's total of 48.5 points 10 times.
• The Rams and their opponents combined to hit the over 10 out of 17 times last season.
• The Giants played eight games last season that ended with a point total over 48.5 points.
• Last season, 11 New York games hit the over.
• The teams combined to score 52.9 points per game last season, 4.4 more points than this matchup's total.
• Combined, these teams allowed 46.2 points per contest last year, 2.3 fewer points than the total for this game.

Betting the Spread: Rams vs. Giants

• Los Angeles won 12 games against the spread last season, failing to cover five times.
• Los Angeles was 4-3 ATS last season when playing as at least 7-point favorites.
• The Giants won nine games against the spread last season, while failing to cover eight times.
• When playing as at least 7-point underdogs last year, New York had an ATS record of 4-2.
• At home last year, the Rams were 6-2 against the spread and 7-1 overall.
• As 7-point favorites or more at home last year, Los Angeles was 3-1 ATS.
• Last season in away games, the Giants were 5-4 against the spread and 1-8 overall.
• New York had two wins ATS (2-2) on the road as 7-point underdogs or more.

Betting the Moneyline: Rams vs. Giants

• Los Angeles put together a 12-3 record in games it was listed as the moneyline favorite last season (winning 80% of those games).
• The Giants won three, or 20%, of the 15 games they played as underdogs last season.
• When it played as a moneyline favorite with odds of -355 or shorter, Los Angeles went 5-3 (62.5%).
• New York was 1-5 last season when entering a game as the underdog by +280 or more on the moneyline.
• The Rams have an implied moneyline win probability of 78.0% in this matchup.

Dunkel Prediction for Rams vs. Giants

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